About: Carotid Intima-media Thickness and Laboratory Parameters of Atherosclerosis Risk in Patients with Breast Cancer

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	To investigate the relation between intima-media thickness (IMT) and laboratory parameters of atherosclerosis risk in patients with breast carcinoma. Patients and Methods: IMT and a panel of laboratory parameters associated with the risk of atherosclerosis were studied in 192 patients with histologically-verified breast carcinoma. Results: Patients with metastatic disease had significantly higher fibrinogen, C-reactive protein (CRP), urinary neopterin and mean IMT, and significantly lower serum albumin and hemoglobin concentrations. Significant correlations were observed between CRP, urinary neopterin, mean IMT and other parameters of cardiovascular risk. Age was an independent predictor of the presence of sonographic signs of atherosclerosis using logistic regression, and age, glucose, time from start of chemotherapy, high-density lipoprotein cholesterol, D-dimers were independently associated with IMT in stepwise regression models. Conclusion: In addition to the associations between IMT and laboratory or clinical parameters of the risk of atherosclerosis, IMT may also be associated with the time from chemotherapy. To investigate the relation between intima-media thickness (IMT) and laboratory parameters of atherosclerosis risk in patients with breast carcinoma. Patients and Methods: IMT and a panel of laboratory parameters associated with the risk of atherosclerosis were studied in 192 patients with histologically-verified breast carcinoma. Results: Patients with metastatic disease had significantly higher fibrinogen, C-reactive protein (CRP), urinary neopterin and mean IMT, and significantly lower serum albumin and hemoglobin concentrations. Significant correlations were observed between CRP, urinary neopterin, mean IMT and other parameters of cardiovascular risk. Age was an independent predictor of the presence of sonographic signs of atherosclerosis using logistic regression, and age, glucose, time from start of chemotherapy, high-density lipoprotein cholesterol, D-dimers were independently associated with IMT in stepwise regression models. Conclusion: In addition to the associations between IMT and laboratory or clinical parameters of the risk of atherosclerosis, IMT may also be associated with the time from chemotherapy. (en)
Title	Carotid Intima-media Thickness and Laboratory Parameters of Atherosclerosis Risk in Patients with Breast Cancer Carotid Intima-media Thickness and Laboratory Parameters of Atherosclerosis Risk in Patients with Breast Cancer (en)
skos:prefLabel	Carotid Intima-media Thickness and Laboratory Parameters of Atherosclerosis Risk in Patients with Breast Cancer Carotid Intima-media Thickness and Laboratory Parameters of Atherosclerosis Risk in Patients with Breast Cancer (en)
skos:notation	RIV/61989592:15110/12:33140634!RIV13-MZ0-15110___
http://linked.open...avai/predkladatel	Lékařská fakulta
http://linked.open...avai/riv/aktivita	I P
http://linked.open...avai/riv/aktivity	I, P(NR9096), P(NT13564)
http://linked.open...iv/cisloPeriodika	9
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Kalábová, Hana Melichar, Bohuslav Študentová, Hana Šrámek, Vlastislav
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Palackého v Olomouci / Lékařská fakulta
http://linked.open...dnocenehoVysledku	126022
http://linked.open...ai/riv/idVysledku	RIV/61989592:15110/12:33140634
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	cardiovascular risk; intima-media thickness; breast cancer; Atherosclerosis (en)
http://linked.open.../riv/klicoveSlovo	Atherosclerosis breast cancer intima-media thickness cardiovascular risk
http://linked.open...odStatuVydavatele	GR - Řecká republika
http://linked.open...ontrolniKodProRIV	[B41B87B62829]
http://linked.open...i/riv/nazevZdroje	Anticancer Research
http://linked.open...in/vavai/riv/obor	FD
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	12 (xsd:int)
http://linked.open...vavai/riv/projekt	Risc factors of atherosclerosis in cancer patients Predictive factors of pathologic response to neoadjuvant chemotherapy in patients with HER-2 positive or triple negative breast carcinoma
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	32
http://linked.open...iv/tvurceVysledku	Hyšpler, Radomír Kalábová, Hana Kašparová, Markéta Krčmová, Lenka Melichar, Bohuslav Pecka, Miroslav Ungermann, Leoš Šrámek, Vlastislav Procházková, Hana Pecen, Ladislav Svobodník, Adam
issn	0250-7005
number of pages	8 (xsd:int)
http://localhost/t...ganizacniJednotka	15110
is http://linked.open...avai/riv/vysledek of	Carotid Intima-media Thickness and Laboratory Parameters of Atherosclerosis Risk in Patients with Breast Cancer

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