About: The first iron(III) complexes with cyclin-dependent kinase inhibitors: Magnetic, spectroscopic (IR, ES+ MS, NMR, Fe-57 Mossbauer), theoretical, and biological activity studies     Goto   Sponge   NotDistinct   Permalink

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  • The first FeIII complexes 1–6 with cyclin-dependent kinase (CDK) inhibitors of the type [Fe(Ln)Cl3]nH2O (n = 0 for 1, 1 for 2, 2 for 3–6; L1–L6 = C2- and phenyl-substituted CDK inhibitors derived from 6-benzylamino-9-isopropylpurine), have been synthesized and characterized by elemental analysis, IR, 57Fe Mössbauer, 1H and 13C NMR, and ES+ mass spectroscopies, conductivity and magnetic susceptibility measurements, and thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC). The study revealed that the compounds are mononuclear, tetrahedral high-spin (S = 5/2) FeIII complexes with an admixture of an S = 3/2 spin state originating probably from five-coordinated FeIII ions either connecting with a bidentate coordination mode of the CDK inhibitor ligand or relating to the possibility that one crystal water molecule enters the coordination sphere of the central atom in a portion of molecules of the appropriate complex.
  • The first FeIII complexes 1–6 with cyclin-dependent kinase (CDK) inhibitors of the type [Fe(Ln)Cl3]nH2O (n = 0 for 1, 1 for 2, 2 for 3–6; L1–L6 = C2- and phenyl-substituted CDK inhibitors derived from 6-benzylamino-9-isopropylpurine), have been synthesized and characterized by elemental analysis, IR, 57Fe Mössbauer, 1H and 13C NMR, and ES+ mass spectroscopies, conductivity and magnetic susceptibility measurements, and thermogravimetric analysis (TGA) and differential scanning calorimetry (DSC). The study revealed that the compounds are mononuclear, tetrahedral high-spin (S = 5/2) FeIII complexes with an admixture of an S = 3/2 spin state originating probably from five-coordinated FeIII ions either connecting with a bidentate coordination mode of the CDK inhibitor ligand or relating to the possibility that one crystal water molecule enters the coordination sphere of the central atom in a portion of molecules of the appropriate complex. (en)
Title
  • The first iron(III) complexes with cyclin-dependent kinase inhibitors: Magnetic, spectroscopic (IR, ES+ MS, NMR, Fe-57 Mossbauer), theoretical, and biological activity studies
  • The first iron(III) complexes with cyclin-dependent kinase inhibitors: Magnetic, spectroscopic (IR, ES+ MS, NMR, Fe-57 Mossbauer), theoretical, and biological activity studies (en)
skos:prefLabel
  • The first iron(III) complexes with cyclin-dependent kinase inhibitors: Magnetic, spectroscopic (IR, ES+ MS, NMR, Fe-57 Mossbauer), theoretical, and biological activity studies
  • The first iron(III) complexes with cyclin-dependent kinase inhibitors: Magnetic, spectroscopic (IR, ES+ MS, NMR, Fe-57 Mossbauer), theoretical, and biological activity studies (en)
skos:notation
  • RIV/61389030:_____/10:00359316!RIV11-GA0-61389030
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(1M0512), P(GA301/08/1649)
http://linked.open...iv/cisloPeriodika
  • 4
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 259287
http://linked.open...ai/riv/idVysledku
  • RIV/61389030:_____/10:00359316
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Iron(III) complexes; 57Fe Mössbauer spectroscopy; CDK inhibition (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [54DD17A5B34F]
http://linked.open...i/riv/nazevZdroje
  • Journal of Inorganic Biochemistry
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 104
http://linked.open...iv/tvurceVysledku
  • Kryštof, Vladimír
  • Trávníček, Zdeněk
  • Popa, Igor
  • Čajan, Michal
  • Zbořil, R.
  • Mikulík, J.
http://linked.open...ain/vavai/riv/wos
  • 000274921200007
issn
  • 0162-0134
number of pages
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