About: Cystathionine .gamma.-lyase: Clinical, metabolic, genetic, and structural studies

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Cystathionine .gamma.-lyase: Clinical, metabolic, genetic, and structural studies Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Paper describes seven genetically inherited mutations of the metabolic protein cystathionine gamma-lyase (h-CTH) found in human and discusses the related clinical symptoms. Levels of metabolites measured in plasma of several hundreds of people with and without mutations are compared. Mutation analysis of 3D molecular structure explains trends of observed effects on metabolites levels and elucidate why vitamin B6 administration improves metabolite levels for some mutations and not for other ones. Paper describes seven genetically inherited mutations of the metabolic protein cystathionine gamma-lyase (h-CTH) found in human and discusses the related clinical symptoms. Levels of metabolites measured in plasma of several hundreds of people with and without mutations are compared. Mutation analysis of 3D molecular structure explains trends of observed effects on metabolites levels and elucidate why vitamin B6 administration improves metabolite levels for some mutations and not for other ones. (en)
Title	Cystathionine .gamma.-lyase: Clinical, metabolic, genetic, and structural studies Cystathionine .gamma.-lyase: Clinical, metabolic, genetic, and structural studies (en)
skos:prefLabel	Cystathionine .gamma.-lyase: Clinical, metabolic, genetic, and structural studies Cystathionine .gamma.-lyase: Clinical, metabolic, genetic, and structural studies (en)
skos:notation	RIV/61389013:_____/09:00370427!RIV12-AV0-61389013
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA305/07/1073), P(IAA500500701), Z(AV0Z40500505), Z(MSM0021620806)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Hašek, Jindřich
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav makromolekulární chemie AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	308805
http://linked.open...ai/riv/idVysledku	RIV/61389013:_____/09:00370427
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	cystathionine gamma-lyase; cystathioninuria; hypercystathioninemia (en)
http://linked.open.../riv/klicoveSlovo	cystathionine gamma-lyase cystathioninuria hypercystathioninemia
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[8A57598A2E56]
http://linked.open...i/riv/nazevZdroje	Molecular Genetics and Metabolism
http://linked.open...in/vavai/riv/obor	CD
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	15 (xsd:int)
http://linked.open...vavai/riv/projekt	Molecular interactions of polymers for biomedical applications Self-organization, crystallization and structure determination of protein based macromolecular systems
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	97
http://linked.open...iv/tvurceVysledku	Hašek, Jindřich Wang, J. Janošíková, B. Kožich, V. Allen, R. H. Chien, Y. H. Collard, R. Finn, C. T. Hegele, R. A. Hwu, W. L. Jakobs, C. Kraus, J. P. Mudd, S. H. Stabler, S. P. Venezia, S.
http://linked.open...ain/vavai/riv/wos	000268156100004
http://linked.open...n/vavai/riv/zamer	Progresivní makromolekulární materiály a supramolekulární systémy: syntéza a studium vlastností, jevů a možností využití pro speciální aplikace a moderní technologie Molekulární biologie a patologie buňky za normy a u vybraných klinicky závažných patologických procesů
issn	1096-7192
number of pages	10 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.ymgme.2009.04.001
is http://linked.open...avai/riv/vysledek of	Cystathionine .gamma.-lyase: Clinical, metabolic, genetic, and structural studies Cystathionine .gamma.-lyase: Clinical, metabolic, genetic, and structural studies

Faceted Search & Find service v1.16.116 as of Feb 22 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3239 as of Feb 22 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 80 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software