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rdf:type
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Description
| - Rpg1p/Tif32p/eIF3a je velká podjednotka eIF3 komplexu fungujícího v iniciaci translace v Saccharomyces cerevisiae.Zjistili jsme, že v nestresovaných buňkách obě, jak GFP tak i mRFP fůze Rpg1p/eIF3a byly rovnoměrně distribuovány v cytoplazmě. Po teplotním šoku Rpg1p/eIF3a akumuloval ve fluoreskujících granulích ve vrcholu pupene a v krčku. Tvorba granulí nebyla závislá na přítomnosti mikrotubulů a aktinu, a nezávisí na Sla2. Předpokládáme, že Rpg1p/eIF3a zprostředkuje tvorbu a rozpuštění stresových granulí. (cs)
- Rpg1p/Tif32p/eIF3a is the large subunit of the eIF3 core complex involved in translation initiation in Saccharomyces cerevisiae.We found that in unstressed cells Rpg1-GFP fusion is uniformly distributed throughout the cytoplasm. Upon osmotic upshift the protein rapidly accumulated in fluorescing foci dispersed in the cytoplasm. Accumulation of Rpg1-GFP fusion was observed near the tip of small buds and at the mother-daughter neck. The formation of Rpg1-GFP granules was not altered by disruption of microtubules or F-actin, and by the absence of Sla2p.We suggest that Rpg1p/eIF3a mediates formation and dissolution of stress granules.
- Rpg1p/Tif32p/eIF3a is the large subunit of the eIF3 core complex involved in translation initiation in Saccharomyces cerevisiae.We found that in unstressed cells Rpg1-GFP fusion is uniformly distributed throughout the cytoplasm. Upon osmotic upshift the protein rapidly accumulated in fluorescing foci dispersed in the cytoplasm. Accumulation of Rpg1-GFP fusion was observed near the tip of small buds and at the mother-daughter neck. The formation of Rpg1-GFP granules was not altered by disruption of microtubules or F-actin, and by the absence of Sla2p.We suggest that Rpg1p/eIF3a mediates formation and dissolution of stress granules. (en)
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Title
| - Rpg1p/elF3a of Saccharomyces cerevisiae accumulates in stress granules
- Rpg1p/elF3a of Saccharomyces cerevisiae accumulates in stress granules (en)
- Rpg1p/elF3a je v Saccharomyces cerevisiae akumulován ve stresových granulích (cs)
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skos:prefLabel
| - Rpg1p/elF3a of Saccharomyces cerevisiae accumulates in stress granules
- Rpg1p/elF3a of Saccharomyces cerevisiae accumulates in stress granules (en)
- Rpg1p/elF3a je v Saccharomyces cerevisiae akumulován ve stresových granulích (cs)
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skos:notation
| - RIV/61388971:_____/04:00107929!RIV/2005/AV0/A53005/N
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http://linked.open.../vavai/riv/strany
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(GA204/02/1424), Z(AV0Z5020903)
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/61388971:_____/04:00107929
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...ontrolniKodProRIV
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http://linked.open...v/mistoKonaniAkce
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http://linked.open...i/riv/mistoVydani
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http://linked.open...i/riv/nazevZdroje
| - Yeast Genetics and Molecular Biology Meeting /2004./
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...iv/tvurceVysledku
| - Hašek, Jiří
- Špryngar, Martin
- Janatová, Ivana
- Kohlwein, S. D.
- Wolinski, H.
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http://linked.open...vavai/riv/typAkce
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http://linked.open.../riv/zahajeniAkce
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http://linked.open...n/vavai/riv/zamer
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number of pages
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http://purl.org/ne...btex#hasPublisher
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