About: New bradykinin B-2 receptor antagonists - influence of C-terminal segment modifications on their pharmacological properties     Goto   Sponge   NotDistinct   Permalink

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  • Analogues of the bradykinin antagonist [D-Arg(0),Hyp(3),Thi(5,8),D-Phe(7)]BK having in position 7 or 8 L-pipecolic acid or L-beta(2)-isoproline or L-beta(3)-homoproline and free or acylated N-terminal amino group were synthesized and biologically evaluated (isolated rat uterus and rat blood pressure tests). The results thus support the hypothesis about the existence of different types of BK receptors in the rat uterus and blood vessels.
  • Analogues of the bradykinin antagonist [D-Arg(0),Hyp(3),Thi(5,8),D-Phe(7)]BK having in position 7 or 8 L-pipecolic acid or L-beta(2)-isoproline or L-beta(3)-homoproline and free or acylated N-terminal amino group were synthesized and biologically evaluated (isolated rat uterus and rat blood pressure tests). The results thus support the hypothesis about the existence of different types of BK receptors in the rat uterus and blood vessels. (en)
Title
  • New bradykinin B-2 receptor antagonists - influence of C-terminal segment modifications on their pharmacological properties
  • New bradykinin B-2 receptor antagonists - influence of C-terminal segment modifications on their pharmacological properties (en)
skos:prefLabel
  • New bradykinin B-2 receptor antagonists - influence of C-terminal segment modifications on their pharmacological properties
  • New bradykinin B-2 receptor antagonists - influence of C-terminal segment modifications on their pharmacological properties (en)
skos:notation
  • RIV/61388963:_____/09:00347364!RIV11-AV0-61388963
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(AV0Z40550506)
http://linked.open...iv/cisloPeriodika
  • 4
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 329322
http://linked.open...ai/riv/idVysledku
  • RIV/61388963:_____/09:00347364
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • bradykinin (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • PL - Polská republika
http://linked.open...ontrolniKodProRIV
  • [EB464731AAE5]
http://linked.open...i/riv/nazevZdroje
  • Acta Biochimica Polonica
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 56
http://linked.open...iv/tvurceVysledku
  • Borovičková, Lenka
  • Slaninová, Jiřina
  • Prahl, A.
  • Sleszynska, M.
  • Sobolewski, D.
  • Wierzba, T. H.
  • Kwiatkowska, A.
  • Katarzynska, J.
  • Zabrocki, J.
http://linked.open...ain/vavai/riv/wos
  • 000276702200008
http://linked.open...n/vavai/riv/zamer
issn
  • 0001-527X
number of pages
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