About: A role of the 9-aminoacridines and their conjugates in a life science

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: A role of the 9-aminoacridines and their conjugates in a life science Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The 9-aminoacridines play an important role in medicine. They were applied first in a treatment of protozoal infections in the beginning of the last century. Recently, it has been shown that the 9-aminoacridines are successful candidates for treatment of cancer, viral and prion diseases. Their conjugation with biomolecules such as peptides and proteins may modulate their activity, bioavailability and applicability. This review deals with the synthesis of 9-aminoacridine, its conjugation with variety of molecules and utilization of such conjugates in several fields of science. The 9-aminoacridines play an important role in medicine. They were applied first in a treatment of protozoal infections in the beginning of the last century. Recently, it has been shown that the 9-aminoacridines are successful candidates for treatment of cancer, viral and prion diseases. Their conjugation with biomolecules such as peptides and proteins may modulate their activity, bioavailability and applicability. This review deals with the synthesis of 9-aminoacridine, its conjugation with variety of molecules and utilization of such conjugates in several fields of science. (en) 9-aminoakridiny hrají významnou úlohu v medicíně. Nejprve byly používány pro léčbu protozoálních infekcí (začátkem předchozího století). Nedávno, byly úspěšně použity proti rakovině, virovým a prionovým onemocněním. Jejich konjugace s biomolekulami může upravit jejich vlastnosti jako je aktivita, biologická dostupnost a použitelnost. V tomto review jsou probrány různé 9-aminoakridiny a jejich deriváty. Diskutována je jejich syntéza, konjugace s biomolekulami a použití v různých oblastech vědy. (cs)
Title	A role of the 9-aminoacridines and their conjugates in a life science A role of the 9-aminoacridines and their conjugates in a life science (en) Úloha 9-aminoakridinu a jejich konjugatu v Life Science (cs)
skos:prefLabel	A role of the 9-aminoacridines and their conjugates in a life science A role of the 9-aminoacridines and their conjugates in a life science (en) Úloha 9-aminoakridinu a jejich konjugatu v Life Science (cs)
skos:notation	RIV/61388963:_____/07:00091205!RIV08-AV0-61388963
http://linked.open.../vavai/riv/strany	471;483
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA203/04/1421), P(GA203/07/1517), Z(AV0Z40550506)
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2008
http://linked.open...aciTvurceVysledku	Šebestík, Jaroslav Hlaváček, Jan
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav organické chemie a biochemie AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	408162
http://linked.open...ai/riv/idVysledku	RIV/61388963:_____/07:00091205
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	acridines; 9-aminoacridine; conjugates; nucleic acids; proteins (en)
http://linked.open.../riv/klicoveSlovo	conjugates proteins 9-aminoacridine nucleic acids acridines
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[B5C740C19E67]
http://linked.open...i/riv/nazevZdroje	Current Protein and Peptide Science
http://linked.open...in/vavai/riv/obor	CC
http://linked.open...ichTvurcuVysledku	2 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	Chemical syntheses of fluorescence labeled mouse prion proteins using chemical ligations and investigation of their properties Visual and/or fluorescent molecular recognition of cyclic nucleotides with azo-bridged cyclic peptide libraries
http://linked.open...UplatneniVysledku	2007
http://linked.open...v/svazekPeriodika	8
http://linked.open...iv/tvurceVysledku	Hlaváček, Jan Šebestík, Jaroslav Stibor, I.
http://linked.open...n/vavai/riv/zamer	Regulace biologických procesů: Chemické modulátory vybraných systémů významných pro medicínu a zemědělství
issn	1389-2037
number of pages	13 (xsd:int)
is http://linked.open...avai/riv/vysledek of	A role of the 9-aminoacridines and their conjugates in a life science A role of the 9-aminoacridines and their conjugates in a life science A role of the 9-aminoacridines and their conjugates in a life science

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 58 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software