About: Mapping of the active site of glutamate carboxypeptidase II by site-directed mutagenesis

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Detailed structural and biochemical analysis of the active site of glutamate carboxypeptidase II was done. Amino acid residues important for substrate/inhibitor binding were determined from a QM/MM model. Detailed structural and biochemical analysis of the active site of glutamate carboxypeptidase II was done. Amino acid residues important for substrate/inhibitor binding were determined from a QM/MM model. (en) Byla provedena podrobná strukturní a biochemická studie aktivního místa glutamát karboxypeptidasy II a identifikovány aminokyseliny důležité pro vazbu substrátu/inhibitoru pomocí modelu QM/MM. (cs)
Title	Mapping of the active site of glutamate carboxypeptidase II by site-directed mutagenesis Mapování aktivního místa glutamát karboxypeptidasy II pomocí místně specifické mutageneze (cs) Mapping of the active site of glutamate carboxypeptidase II by site-directed mutagenesis (en)
skos:prefLabel	Mapping of the active site of glutamate carboxypeptidase II by site-directed mutagenesis Mapování aktivního místa glutamát karboxypeptidasy II pomocí místně specifické mutageneze (cs) Mapping of the active site of glutamate carboxypeptidase II by site-directed mutagenesis (en)
skos:notation	RIV/61388963:_____/07:00089022!RIV08-AV0-61388963
http://linked.open.../vavai/riv/strany	4731;4741
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1M0508), P(LC512), Z(AV0Z40550506), Z(MSM 113100001)
http://linked.open...iv/cisloPeriodika	18
http://linked.open...vai/riv/dodaniDat	2008
http://linked.open...aciTvurceVysledku	Mlčochová, Petra Rulíšek, Lubomír Plechanovová, Anna Konvalinka, Jan
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ústav organické chemie a biochemie AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	432093
http://linked.open...ai/riv/idVysledku	RIV/61388963:_____/07:00089022
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	NAALADase; PSMA; metallopeptidase; active-site; mutagenesis (en)
http://linked.open.../riv/klicoveSlovo	mutagenesis active-site PSMA metallopeptidase NAALADase
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[1AABDD75C627]
http://linked.open...i/riv/nazevZdroje	FEBS Journal
http://linked.open...in/vavai/riv/obor	CE
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	New Antivirals and Antineoplastics Center for biomolecules and complex molecular systems
http://linked.open...UplatneniVysledku	2007
http://linked.open...v/svazekPeriodika	274
http://linked.open...iv/tvurceVysledku	Konvalinka, Jan Rulíšek, Lubomír Mlčochová, Petra Plechanovová, Anna Bařinka, C. Mahadevan, D. Saldanha, J. W.
http://linked.open...n/vavai/riv/zamer	Regulace biologických procesů: Chemické modulátory vybraných systémů významných pro medicínu a zemědělství http://linked.opendata.cz/resource/domain/vavai/zamer/MSM%20113100001
issn	1742-464X
number of pages	11 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Mapping of the active site of glutamate carboxypeptidase II by site-directed mutagenesis Mapping of the active site of glutamate carboxypeptidase II by site-directed mutagenesis Mapping of the active site of glutamate carboxypeptidase II by site-directed mutagenesis

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