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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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Description
  • The work describes a new mechanism of drug resistence development towards protease inhibitors as HIV therapy. Mechanism is based on accumulation of mutations in Gag polyprotein near the places which are cleaved by the protease.
  • The work describes a new mechanism of drug resistence development towards protease inhibitors as HIV therapy. Mechanism is based on accumulation of mutations in Gag polyprotein near the places which are cleaved by the protease. (en)
  • Práce popisuje nový mechanismus vzniku rezistence vůči inhibitorům proteasy jako lékům proti HIV. Mechanismus spočívá v akumulaci mutací v polyproteinu Gag v sousedství míst, která jsou proteasou štěpena. (cs)
Title
  • A novel substrate-based HIV-1 protease inhibitor drug resistance mechanism
  • A novel substrate-based HIV-1 protease inhibitor drug resistance mechanism (en)
  • Nový mechanismus vzniku rezistence vůči inhibitorům proteasy HIV-1 založený na substrátu (cs)
skos:prefLabel
  • A novel substrate-based HIV-1 protease inhibitor drug resistance mechanism
  • A novel substrate-based HIV-1 protease inhibitor drug resistance mechanism (en)
  • Nový mechanismus vzniku rezistence vůči inhibitorům proteasy HIV-1 založený na substrátu (cs)
skos:notation
  • RIV/61388963:_____/07:00084111!RIV08-AV0-61388963
http://linked.open.../vavai/riv/strany
  • 152;163
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(AV0Z40550506), Z(MSM 113100001)
http://linked.open...iv/cisloPeriodika
  • 1
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 437926
http://linked.open...ai/riv/idVysledku
  • RIV/61388963:_____/07:00084111
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • HIV-1 protease; drug resistance; protease inhibitor (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [CA7ADB6423C9]
http://linked.open...i/riv/nazevZdroje
  • PLoS MEDICINE
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 4
http://linked.open...iv/tvurceVysledku
  • Konvalinka, Jan
  • Kräusslich, H. G.
  • Maarseveen van, N. M.
  • Nijhuis, M.
  • Boucher, Ch. A. B.
  • Jong de, D.
  • Glass, B.
  • Rovenská, Miroslava
  • Brakier-Gingras, L.
  • Brun-Vezinet, F.
  • Cammack, N.
  • Chappey, C.
  • Coakley, E.
  • Dulude, D.
  • Goedegebuure, I. W.
  • Heilek-Snyder, G.
  • Lastere, S.
  • Parkin, N.
  • Schipper, P.
http://linked.open...n/vavai/riv/zamer
issn
  • 1549-1277
number of pages
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