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Description
  • An efficient synthesis of 6-azapregnane derivatives and their biological activity is described. The nitrogen was introduced into the B ring using Beckmann rearrangement of the (E)-oxime of 6-oxo-B-nor-5alpha-pregnane derivatives.
  • An efficient synthesis of 6-azapregnane derivatives and their biological activity is described. The nitrogen was introduced into the B ring using Beckmann rearrangement of the (E)-oxime of 6-oxo-B-nor-5alpha-pregnane derivatives. (en)
  • Je popsána účinná syntéza 6-azapregnanových derivátů a jejich biologická aktivita. Atom dusíku je vpravován do kruhu B pomocí Beckmannova přesmyku (E)-oximu 6-oxo-B-norpregnanových meziproduktů. Požadovaný 3alfa-hydroxyl je zaváděn buď solvolýzou 3beta-mesylátů nebo redukcí 3-ketonů dle Meerwein-Ponndof-Verleye. Cílová látka účinná není, ale její 3-deoxyderivát ano. (cs)
Title
  • Neurosteroid analogues: synthesis of 6-aza-allopregnanolone
  • Analogy neurosteroidů: syntéza 6-aza-allopregnanolonu (cs)
  • Neurosteroid analogues: synthesis of 6-aza-allopregnanolone (en)
skos:prefLabel
  • Neurosteroid analogues: synthesis of 6-aza-allopregnanolone
  • Analogy neurosteroidů: syntéza 6-aza-allopregnanolonu (cs)
  • Neurosteroid analogues: synthesis of 6-aza-allopregnanolone (en)
skos:notation
  • RIV/61388963:_____/05:00020928!RIV06-AV0-61388963
http://linked.open.../vavai/riv/strany
  • 2269;2278
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(IBS5011007), Z(AV0Z40550506)
http://linked.open...iv/cisloPeriodika
  • 9
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 532586
http://linked.open...ai/riv/idVysledku
  • RIV/61388963:_____/05:00020928
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • 6-azasteroids; Beckmann rearrangement; NMR spectroscopy (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [F1D4FDD498D8]
http://linked.open...i/riv/nazevZdroje
  • Tetrahedron
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 61
http://linked.open...iv/tvurceVysledku
  • Buděšínský, Miloš
  • Kasal, Alexander
  • Matyáš, Libor
http://linked.open...n/vavai/riv/zamer
issn
  • 0040-4020
number of pages
is http://linked.open...avai/riv/vysledek of
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