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  • Mechanisms of water flow across the peritoneal membrane include diffusion, convection and reabsorption. To understand these processes more clearly we have developed a method to measure transport of water across the peritoneal membrane. An artificial gradient of deuterated water (HDO) between blood and dialysate compartments was created in 5 subjects who took 0.3g per kg of body weight of D2O, which was allowed to equilibrate with total body water. During a test dwell (2L, bicarbonate:lactate buffer, 1.36% glucose to minimise convection), frequent dialysate samples were drawn to determine the abundance of deuterium and other solutes and to calculate their time constants. Dialysate deuterium abundance was measured using flowing afterglow mass spectrometry, FA-MS.
  • Mechanisms of water flow across the peritoneal membrane include diffusion, convection and reabsorption. To understand these processes more clearly we have developed a method to measure transport of water across the peritoneal membrane. An artificial gradient of deuterated water (HDO) between blood and dialysate compartments was created in 5 subjects who took 0.3g per kg of body weight of D2O, which was allowed to equilibrate with total body water. During a test dwell (2L, bicarbonate:lactate buffer, 1.36% glucose to minimise convection), frequent dialysate samples were drawn to determine the abundance of deuterium and other solutes and to calculate their time constants. Dialysate deuterium abundance was measured using flowing afterglow mass spectrometry, FA-MS. (en)
Title
  • Measuring Transport of Water Across the Peritoneal Membrane.
  • Measuring Transport of Water Across the Peritoneal Membrane. (en)
skos:prefLabel
  • Measuring Transport of Water Across the Peritoneal Membrane.
  • Measuring Transport of Water Across the Peritoneal Membrane. (en)
skos:notation
  • RIV/61388955:_____/03:54030270!RIV/2004/AV0/A54004/N
http://linked.open.../vavai/riv/strany
  • 1911;1915
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA202/03/0827), Z(AV0Z4040901)
http://linked.open...iv/cisloPeriodika
  • N/A
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 614641
http://linked.open...ai/riv/idVysledku
  • RIV/61388955:_____/03:54030270
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • deuterium; total body water; solute transport (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV
  • [BA257C841498]
http://linked.open...i/riv/nazevZdroje
  • Kidney International
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...ocetUcastnikuAkce
http://linked.open...nichUcastnikuAkce
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 64
http://linked.open...iv/tvurceVysledku
  • Smith, D.
  • Španěl, Patrik
  • Davies, S. J.
  • Asghar, R. B.
  • Diskin, A. M.
http://linked.open...n/vavai/riv/zamer
issn
  • 0085-2538
number of pages
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