About: Regulation or activity of protease of mason-Pfizer monkey virus     Goto   Sponge   NotDistinct   Permalink

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Description
  • In Mason-Pfizer monkey virus the assembly of immature capsids and the cleavage of polyprotein precursors are temporary and spatially separated processes making the virus an attractive model for investigation of protease activation. Here we present a highresolution NMR structure of fully folded monomer of Cys7/Ala, Asp26/Asn., Cys 106/Ala mutant of the 12kDa MPMV protease. The overall structures of both wt PR follow the conservative structural motif of other retroviral proteases.
  • In Mason-Pfizer monkey virus the assembly of immature capsids and the cleavage of polyprotein precursors are temporary and spatially separated processes making the virus an attractive model for investigation of protease activation. Here we present a highresolution NMR structure of fully folded monomer of Cys7/Ala, Asp26/Asn., Cys 106/Ala mutant of the 12kDa MPMV protease. The overall structures of both wt PR follow the conservative structural motif of other retroviral proteases. (en)
Title
  • Regulation or activity of protease of mason-Pfizer monkey virus
  • Regulation or activity of protease of mason-Pfizer monkey virus (en)
skos:prefLabel
  • Regulation or activity of protease of mason-Pfizer monkey virus
  • Regulation or activity of protease of mason-Pfizer monkey virus (en)
skos:notation
  • RIV/60461373:22640/03:00008355!RIV/2004/GA0/226404/N
http://linked.open.../vavai/riv/strany
  • 47
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA203/00/1241), P(LN00A079)
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 625083
http://linked.open...ai/riv/idVysledku
  • RIV/60461373:22640/03:00008355
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • activity of protedase MPMV, NMR structure, stabilizing dimer (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [0FFF86BFE891]
http://linked.open...v/mistoKonaniAkce
  • Sardegna
http://linked.open...i/riv/mistoVydani
  • Sardegna
http://linked.open...i/riv/nazevZdroje
  • Fourth International Virus Assembly Symposium, Programme and Abstracts
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...ocetUcastnikuAkce
http://linked.open...nichUcastnikuAkce
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...iv/tvurceVysledku
  • Pichová, Iva
  • Hrabal, Richard
  • Lang, Jan
  • Ruml, Tomáš
  • Veverka, Václav
  • Bauerová, Helena
  • Zábranský, Aleš
http://linked.open...vavai/riv/typAkce
http://linked.open.../riv/zahajeniAkce
number of pages
http://purl.org/ne...btex#hasPublisher
  • Italian Association of Chemical Engineering
http://localhost/t...ganizacniJednotka
  • 22640
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