About: A proteomic view of the host-pathogen interaction: The host perspective

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://dx.doi.org/10.1002/pmic.201000767
Description	The host-pathogen interaction represents a complex and dynamic biological system. The outcome of this interaction is dependent on the microbial pathogen properties to establish infection and the ability of the host to control infection. Although bacterial pathogens have evolved a variety of strategies to subvert host defense functions, several general mechanisms have been shown to be shared among these pathogens. As a result, host effectors that are critical for pathogen entry, survival and replication inside the host cells have become a new paradigm for antimicrobial targeting. This review focuses on the potential utility of a proteomics approach in defining the host-pathogen interaction from the host's perspective. The host-pathogen interaction represents a complex and dynamic biological system. The outcome of this interaction is dependent on the microbial pathogen properties to establish infection and the ability of the host to control infection. Although bacterial pathogens have evolved a variety of strategies to subvert host defense functions, several general mechanisms have been shown to be shared among these pathogens. As a result, host effectors that are critical for pathogen entry, survival and replication inside the host cells have become a new paradigm for antimicrobial targeting. This review focuses on the potential utility of a proteomics approach in defining the host-pathogen interaction from the host's perspective. (en)
Title	A proteomic view of the host-pathogen interaction: The host perspective A proteomic view of the host-pathogen interaction: The host perspective (en)
skos:prefLabel	A proteomic view of the host-pathogen interaction: The host perspective A proteomic view of the host-pathogen interaction: The host perspective (en)
skos:notation	RIV/60162694:G44__/11:00002483!RIV12-MO0-G44_____
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(OVUOFVZ200808), Z(MO0FVZ0000501)
http://linked.open...iv/cisloPeriodika	15
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Kročová, Zuzana Červený, Lukáš Stulík, Jiří Härtlová, Anetta
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Ministerstvo obrany / Univerzita obrany - Fakulta vojenského zdravotnictví Hradec Králové
http://linked.open...dnocenehoVysledku	184086
http://linked.open...ai/riv/idVysledku	RIV/60162694:G44__/11:00002483
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Host-pathogen interaction; Host response; Microbiology; MS (en)
http://linked.open.../riv/klicoveSlovo	Host response Host-pathogen interaction MS Microbiology
http://linked.open...odStatuVydavatele	DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV	[7C3D7EE30F81]
http://linked.open...i/riv/nazevZdroje	Proteomics
http://linked.open...in/vavai/riv/obor	EE
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Development of new prophylactic tools against Francisella tularensis infection
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	11
http://linked.open...iv/tvurceVysledku	Härtlová, Anetta Kročová, Zuzana Stulík, Jiří Červený, Lukáš
http://linked.open...ain/vavai/riv/wos	000293269100024
http://linked.open...n/vavai/riv/zamer	Zdravotnická problematika ZHN
issn	1615-9853
number of pages	9 (xsd:int)
http://localhost/t...ganizacniJednotka	G44
is http://linked.open...avai/riv/vysledek of	A proteomic view of the host-pathogen interaction: The host perspective

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