About: Tick as a Model for the Study of a Primitive Complement System

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Ticks are blood feeding parasites transmitting a wide variety of pathogens to their vertebrate hosts. The transmitted pathogens apparently evolved efficient mechanisms enabling them to evade or withstand the cellular or humoral immune responses within the tick vector. Despite its importance, our knowledge of tick innate immunity still lags far beyond other well established invertebrate models, such as drosophila, horseshoe crab or mosquitoes. However, the recent release of the American deer tick, Ixodes scapularis, genome and feasibility of functional analysis based on RNA interference (RNAi) facilitate the development of this organism as a full-value model for deeper studies of vector-pathogen interactions. Ticks are blood feeding parasites transmitting a wide variety of pathogens to their vertebrate hosts. The transmitted pathogens apparently evolved efficient mechanisms enabling them to evade or withstand the cellular or humoral immune responses within the tick vector. Despite its importance, our knowledge of tick innate immunity still lags far beyond other well established invertebrate models, such as drosophila, horseshoe crab or mosquitoes. However, the recent release of the American deer tick, Ixodes scapularis, genome and feasibility of functional analysis based on RNA interference (RNAi) facilitate the development of this organism as a full-value model for deeper studies of vector-pathogen interactions. (en)
Title	Tick as a Model for the Study of a Primitive Complement System Tick as a Model for the Study of a Primitive Complement System (en)
skos:prefLabel	Tick as a Model for the Study of a Primitive Complement System Tick as a Model for the Study of a Primitive Complement System (en)
skos:notation	RIV/60077344:_____/13:00389980!RIV13-GA0-60077344
http://linked.open...avai/predkladatel	Biologické centrum AV ČR, v. v. i.
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GAP506/10/2136), P(LC06009), Z(AV0Z60220518)
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Kopáček, Petr Burešová, Veronika Hajdušek, Ondřej
http://linked.open.../riv/druhVysledku	C - Kapitola v knize
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Biologické centrum AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	111069
http://linked.open...ai/riv/idVysledku	RIV/60077344:_____/13:00389980
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	vector anopheles-gambiae; Ornithodoros moubata; Ixodes ricinus; innate immunity; dorim M; Chryseobacterium indologenes; molecular characterization; component C3; phagocytosis P; hemocytes (en)
http://linked.open.../riv/klicoveSlovo	Ixodes ricinus innate immunity molecular characterization Chryseobacterium indologenes Ornithodoros moubata component C3 dorim M hemocytes phagocytosis P vector anopheles-gambiae
http://linked.open...ontrolniKodProRIV	[1C71C036927C]
http://linked.open...i/riv/mistoVydani	Berlin
http://linked.open...i/riv/nazevZdroje	Recent Advances on Model Hosts
http://linked.open...in/vavai/riv/obor	EB
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...v/pocetStranKnihy	136 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	Centre for molecular ecology of vectors and pathogens Functional genomics of the complement-like molecules in the tick Ixodes ricinus
http://linked.open...UplatneniVysledku	2013
http://linked.open...iv/tvurceVysledku	Kopáček, Petr Burešová, Veronika Hajdušek, Ondřej
http://linked.open...n/vavai/riv/zamer	Parazitismus a parazito-hostitelské vztahy na organismální, buněčné a molekulové úrovni
number of pages	11 (xsd:int)
http://bibframe.org/vocab/doi	10.1007/978-1-4419-5638-5_9
http://purl.org/ne...btex#hasPublisher	Springer-Verlag
https://schema.org/isbn	978-1-4419-5638-5

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