About: Tick saliva affects both proliferation and distribution of Borrelia burgdorferi spirochetes in mouse organs and increases transmission of spirochetes to ticks

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About: Tick saliva affects both proliferation and distribution of Borrelia burgdorferi spirochetes in mouse organs and increases transmission of spirochetes to ticks Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The influence of the feeding of uninfected Ixodes ricinus nymphs on the proliferation and distribution of Borrelia burgdorferi spirochetes was compared with the effect of coinoculated saliva or salivary gland extract (SGE). SGE significantly increased spirochete numbers in the skin 4 and 6 dpi, but decreased bacterial load in the heart compared to control animals. The inoculation of tick saliva increased spirochete load in the urinary bladder 6 dpi, while the number of spirochetes in the heart declined. The nymph feeding raised spirochete load in the bladder 4 and 6 dpi. On day 6, the number of spirochetes in the heart was significantly lower than in controls. The prevalence of spirochetes in ticks infected by feeding on mice was 10 higher when the mice were infected with spirochetes and saliva or SGE, in comparison with spirochetes alone. The presence of SGE in the inoculum increased spirochete burden per tick from 0 to almost 28000. The influence of the feeding of uninfected Ixodes ricinus nymphs on the proliferation and distribution of Borrelia burgdorferi spirochetes was compared with the effect of coinoculated saliva or salivary gland extract (SGE). SGE significantly increased spirochete numbers in the skin 4 and 6 dpi, but decreased bacterial load in the heart compared to control animals. The inoculation of tick saliva increased spirochete load in the urinary bladder 6 dpi, while the number of spirochetes in the heart declined. The nymph feeding raised spirochete load in the bladder 4 and 6 dpi. On day 6, the number of spirochetes in the heart was significantly lower than in controls. The prevalence of spirochetes in ticks infected by feeding on mice was 10 higher when the mice were infected with spirochetes and saliva or SGE, in comparison with spirochetes alone. The presence of SGE in the inoculum increased spirochete burden per tick from 0 to almost 28000. (en)
Title	Tick saliva affects both proliferation and distribution of Borrelia burgdorferi spirochetes in mouse organs and increases transmission of spirochetes to ticks Tick saliva affects both proliferation and distribution of Borrelia burgdorferi spirochetes in mouse organs and increases transmission of spirochetes to ticks (en)
skos:prefLabel	Tick saliva affects both proliferation and distribution of Borrelia burgdorferi spirochetes in mouse organs and increases transmission of spirochetes to ticks Tick saliva affects both proliferation and distribution of Borrelia burgdorferi spirochetes in mouse organs and increases transmission of spirochetes to ticks (en)
skos:notation	RIV/60077344:_____/09:00334910!RIV10-MSM-60077344
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(IAA600960811), P(LC06009), Z(AV0Z60220518), Z(MSM6007665801)
http://linked.open...iv/cisloPeriodika	5
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Kopecký, Jan Horká, Helena Černá, Kateřina Fialová, Anna
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Biologické centrum AV ČR, v. v. i.
http://linked.open...dnocenehoVysledku	346329
http://linked.open...ai/riv/idVysledku	RIV/60077344:_____/09:00334910
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Borrelia burgdorferi; Ixodes ricinus; saliva-activated transmission; real-time PCR (en)
http://linked.open.../riv/klicoveSlovo	Ixodes ricinus real-time PCR Borrelia burgdorferi saliva-activated transmission
http://linked.open...odStatuVydavatele	DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV	[1E104E472475]
http://linked.open...i/riv/nazevZdroje	International Journal of Medical Microbiology
http://linked.open...in/vavai/riv/obor	EC
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...vavai/riv/projekt	Identification of tick salivary molecules facilitating transmission of Borrelia burgdorferi using RNA interference Centre for molecular ecology of vectors and pathogens
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	299
http://linked.open...iv/tvurceVysledku	Kopecký, Jan Horká, Helena Skallová, Anna Černá-Kýčková, Kateřina
http://linked.open...ain/vavai/riv/wos	000267688600007
http://linked.open...n/vavai/riv/zamer	Parazitismus a parazito-hostitelské vztahy na organismální, buněčné a molekulové úrovni EKOLOGICKÉ, EVOLUČNÍ A EXPERIMENTÁLNĚ BIOLOGICKÉ PŘÍSTUPY KE STUDIU VZNIKU A VÝZNAMU BIODIVERZITY
issn	1438-4221
number of pages	8 (xsd:int)
is http://linked.open...avai/riv/vysledek of	Tick saliva affects both proliferation and distribution of Borrelia burgdorferi spirochetes in mouse organs and increases transmission of spirochetes to ticks Tick saliva affects both proliferation and distribution of Borrelia burgdorferi spirochetes in mouse organs and increases transmission of spirochetes to ticks Tick saliva affects both proliferation and distribution of Borrelia burgdorferi spirochetes in mouse organs and increases transmission of spirochetes to ticks Tick saliva affects both proliferation and distribution of Borrelia burgdorferi spirochetes in mouse organs and increases transmission of spirochetes to ticks

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