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rdf:type
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Description
| - Frataxin is a conserved mitochondrial protein, almost universally present in prokaryotes and eukaryotes, where it is implicated in Fe-S cluster assembly and several other processes. Here we show that frataxins from the diatom Thalassiosira pseudonana and the plant Arabidopsis thaliana are efficiently targeted and processed in the mitochondrion of the evolutionary distant excavate kinetoplastid flagellate Trypanosoma brucei. Moreover, both heterologous frataxins are able to rescue a lethal deficiency for T. brucei frataxin.
- Frataxin is a conserved mitochondrial protein, almost universally present in prokaryotes and eukaryotes, where it is implicated in Fe-S cluster assembly and several other processes. Here we show that frataxins from the diatom Thalassiosira pseudonana and the plant Arabidopsis thaliana are efficiently targeted and processed in the mitochondrion of the evolutionary distant excavate kinetoplastid flagellate Trypanosoma brucei. Moreover, both heterologous frataxins are able to rescue a lethal deficiency for T. brucei frataxin. (en)
- Frataxin je konzervovaný mitochondriální protein, všudypřítomný u prokaryot a eukaryot, kde se zúčastňuje tvorby Fe-S klasterů a dalších procesů. V této práci ukazujeme, že frataxin z rozsivky Thalassiosira pseudonana a rostliny Arabidopsis thaliana je efektivně vnášen a upravován v mitochondrii evolučně vzdáleného kinetoplastidového bičíkovce Trypanosoma brucei. Navíc byly oba heterologní frataxiny schopny zachránit smrtelnou deficienci frataxinu v T. brucei. (cs)
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Title
| - The import and function of diatom and plant frataxins in the mitochondrion of Trypanosoma brucei
- The import and function of diatom and plant frataxins in the mitochondrion of Trypanosoma brucei (en)
- Import a funkce rozsivkového a rostlinného frataxinu v mitochondrii Trypanosoma brucei (cs)
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skos:prefLabel
| - The import and function of diatom and plant frataxins in the mitochondrion of Trypanosoma brucei
- The import and function of diatom and plant frataxins in the mitochondrion of Trypanosoma brucei (en)
- Import a funkce rozsivkového a rostlinného frataxinu v mitochondrii Trypanosoma brucei (cs)
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skos:notation
| - RIV/60077344:_____/08:00318325!RIV09-GA0-60077344
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(2B06129), P(GA204/06/1558), P(IAA500960705), P(LC07032), Z(AV0Z60220518)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/60077344:_____/08:00318325
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - frataxin; mitochondrion; Trypanosoma; diatom; evolutionary conservativeness; import (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
| - Molecular and Biochemical Parasitology
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Lukeš, Julius
- Vávrová, Zuzana
- Long, Shaojun
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http://linked.open...ain/vavai/riv/wos
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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is http://linked.open...avai/riv/vysledek
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