About: Unusual Interstrand Pt(S,S-diaminocyclohexane)-GG Crosslink Formed by Rearrangement of a Classical Intrastrand Crosslink Within a DNA Duplex     Goto   Sponge   NotDistinct   Permalink

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Description
  • An unusual G6G11interstrand crosslink is formed by spontaneous rearrangement of the canonical G5G6 intrastrand crosslink generated from the DNA duplex d(CCTTG5G6T7C8TC)-d(G11AGACCAAGG) and Pt(S,S-diaminocyclohexane)2+ (the enantiomer of the antitumor drug oxaliplatin). The final product provides a rare example of intramolecular self-intercalation of DNA.
  • An unusual G6G11interstrand crosslink is formed by spontaneous rearrangement of the canonical G5G6 intrastrand crosslink generated from the DNA duplex d(CCTTG5G6T7C8TC)-d(G11AGACCAAGG) and Pt(S,S-diaminocyclohexane)2+ (the enantiomer of the antitumor drug oxaliplatin). The final product provides a rare example of intramolecular self-intercalation of DNA. (en)
Title
  • Unusual Interstrand Pt(S,S-diaminocyclohexane)-GG Crosslink Formed by Rearrangement of a Classical Intrastrand Crosslink Within a DNA Duplex
  • Unusual Interstrand Pt(S,S-diaminocyclohexane)-GG Crosslink Formed by Rearrangement of a Classical Intrastrand Crosslink Within a DNA Duplex (en)
skos:prefLabel
  • Unusual Interstrand Pt(S,S-diaminocyclohexane)-GG Crosslink Formed by Rearrangement of a Classical Intrastrand Crosslink Within a DNA Duplex
  • Unusual Interstrand Pt(S,S-diaminocyclohexane)-GG Crosslink Formed by Rearrangement of a Classical Intrastrand Crosslink Within a DNA Duplex (en)
skos:notation
  • RIV/60076658:12310/10:00011900!RIV11-MSM-12310___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GP202/08/P416), S, V, Z(AV0Z60220518)
http://linked.open...iv/cisloPeriodika
  • 2
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 294424
http://linked.open...ai/riv/idVysledku
  • RIV/60076658:12310/10:00011900
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • DNA structures; interstrand crosslinks; molecular modeling; NMR spectroscopy; platinum (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV
  • [CA31839B25C5]
http://linked.open...i/riv/nazevZdroje
  • Chemistry-An Asian Journal
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 5
http://linked.open...iv/tvurceVysledku
  • Kozelka, Jiří
  • Kubíček, Karel
  • Arnesano, Fabio
  • Natile, Giovanni
  • Kopečná, Jana
  • Monnet, Jordan
  • Trantírek, Lukáš
  • Chopard, Claude
  • Scintilla, Simone
http://linked.open...ain/vavai/riv/wos
  • 000274539100003
http://linked.open...n/vavai/riv/zamer
issn
  • 1861-4728
number of pages
http://localhost/t...ganizacniJednotka
  • 12310
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