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  • A three-dimensional finite element model of a vascular smooth muscle cell is based on models published recently; it comprehends elements representing cell membrane, cytoplasm and nucleus, and a complex tensegrity structure representing the cytoskeleton. In contrast to previous models of eucaryotic cells, this tensegrity structure consists of several parts. Its external and internal parts number 30 struts, 60 cables each, and their nodes are interconnected by 30 radial members; these parts represent cortical, nuclear and deep cytoskeletons, respectively. This arrangement enables us to simulate load transmission from the extracellular space to the nucleus or centrosome via membrane receptors (focal adhesions); the ability of the model was tested by simulation of some mechanical tests with isolated vascular smooth muscle cells. Although material properties of components defined on the basis of the mechanical tests are ambiguous, modelling of different types of tests has shown the ability of the model to
  • A three-dimensional finite element model of a vascular smooth muscle cell is based on models published recently; it comprehends elements representing cell membrane, cytoplasm and nucleus, and a complex tensegrity structure representing the cytoskeleton. In contrast to previous models of eucaryotic cells, this tensegrity structure consists of several parts. Its external and internal parts number 30 struts, 60 cables each, and their nodes are interconnected by 30 radial members; these parts represent cortical, nuclear and deep cytoskeletons, respectively. This arrangement enables us to simulate load transmission from the extracellular space to the nucleus or centrosome via membrane receptors (focal adhesions); the ability of the model was tested by simulation of some mechanical tests with isolated vascular smooth muscle cells. Although material properties of components defined on the basis of the mechanical tests are ambiguous, modelling of different types of tests has shown the ability of the model to (en)
Title
  • Tensegrity finite element models of mechanical tests of individual cells
  • Tensegrity finite element models of mechanical tests of individual cells (en)
skos:prefLabel
  • Tensegrity finite element models of mechanical tests of individual cells
  • Tensegrity finite element models of mechanical tests of individual cells (en)
skos:notation
  • RIV/00216305:26210/12:PU96461!RIV13-GA0-26210___
http://linked.open...avai/predkladatel
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  • P(GA106/09/1732)
http://linked.open...iv/cisloPeriodika
  • 2
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http://linked.open...aciTvurceVysledku
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  • 173752
http://linked.open...ai/riv/idVysledku
  • RIV/00216305:26210/12:PU96461
http://linked.open...riv/jazykVysledku
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  • Cell biomechanics, Tensegrity structure, Cytoskeleton, Computational model (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • NL - Nizozemsko
http://linked.open...ontrolniKodProRIV
  • [0F2A59B48A6D]
http://linked.open...i/riv/nazevZdroje
  • Technology and Health Care, Int. Journal of Health Care Engineering
http://linked.open...in/vavai/riv/obor
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http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 20
http://linked.open...iv/tvurceVysledku
  • Burša, Jiří
  • Holata, Jakub
  • Lebiš, Radek
issn
  • 0928-7329
number of pages
http://localhost/t...ganizacniJednotka
  • 26210
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