About: Problematic glycosyltransferase Rv3782 from Mycobacterium tuberculosis and its production in new expression system     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
Description
  • Mycobacterium tuberculosis is germ causing one of the most difficultly treated and in many cases lethal infectious disease – tuberculosis. This pathogenic bacterium is characterized by unique cell envelope – dominant feature of M. tuberculosis and other mycobacterial pathogens and crucial factor of virulence and resistance against toxic insult, such as antibiotics and components of the macrophage's bactericidal arsenal. The synthesis of this mycobacterial cell wall is mediated by dominating group of enzymes – glycosyltransferases. Rv3782 is mycobacterial glycosyltransferase which is responsible for synthesis of mycobacterial galactan - very important element of mycobacterial cell wall and its lack can cause growth inhibition up to death. Due to its role in the cell wall synthesis, the Rv3782 galactofuranosyltransferase may represent very attractive target for new drug development against tuberculosis.
  • Mycobacterium tuberculosis is germ causing one of the most difficultly treated and in many cases lethal infectious disease – tuberculosis. This pathogenic bacterium is characterized by unique cell envelope – dominant feature of M. tuberculosis and other mycobacterial pathogens and crucial factor of virulence and resistance against toxic insult, such as antibiotics and components of the macrophage's bactericidal arsenal. The synthesis of this mycobacterial cell wall is mediated by dominating group of enzymes – glycosyltransferases. Rv3782 is mycobacterial glycosyltransferase which is responsible for synthesis of mycobacterial galactan - very important element of mycobacterial cell wall and its lack can cause growth inhibition up to death. Due to its role in the cell wall synthesis, the Rv3782 galactofuranosyltransferase may represent very attractive target for new drug development against tuberculosis. (en)
Title
  • Problematic glycosyltransferase Rv3782 from Mycobacterium tuberculosis and its production in new expression system
  • Problematic glycosyltransferase Rv3782 from Mycobacterium tuberculosis and its production in new expression system (en)
skos:prefLabel
  • Problematic glycosyltransferase Rv3782 from Mycobacterium tuberculosis and its production in new expression system
  • Problematic glycosyltransferase Rv3782 from Mycobacterium tuberculosis and its production in new expression system (en)
skos:notation
  • RIV/00216224:14740/12:00060507!RIV13-MSM-14740___
http://linked.open...avai/predkladatel
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • S, Z(MSM0021622413)
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 162152
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14740/12:00060507
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • glycosyltransferase Rv378 vector pMTW (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...ontrolniKodProRIV
  • [53AEC29DCB58]
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...iv/tvurceVysledku
  • Kostlánová, Nikola
  • Wimmerová, Michaela
  • Jančaříková, Gita
http://linked.open...n/vavai/riv/zamer
http://localhost/t...ganizacniJednotka
  • 14740
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 110 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software