About: Interaction of Notch and gp130 Signaling in the Maintenance of Neural Stem and Progenitor Cells     Goto   Sponge   NotDistinct   Permalink

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  • Notch and gp130 signaling are involved in the regulation of multiple cellular processes across various tissues during animal ontogenesis. In the developing nervous system, both signaling pathways intervene at many stages to determine cell fate-from the first neural lineage commitment and generation of neuronal precursors, to the terminal specification of cells as neurons and glia. In most cases, the effects of Notch and gp130 signaling in these processes are similar. The aim of the current review was to summarize the knowledge regarding the roles of Notch and gp130 signaling in the maintenance of neural stem and progenitor cells during animal ontogenesis, from early embryo to adult. Recent data show a direct crosstalk between these signaling pathways that seems to be specific for a particular type of neural progenitors.
  • Notch and gp130 signaling are involved in the regulation of multiple cellular processes across various tissues during animal ontogenesis. In the developing nervous system, both signaling pathways intervene at many stages to determine cell fate-from the first neural lineage commitment and generation of neuronal precursors, to the terminal specification of cells as neurons and glia. In most cases, the effects of Notch and gp130 signaling in these processes are similar. The aim of the current review was to summarize the knowledge regarding the roles of Notch and gp130 signaling in the maintenance of neural stem and progenitor cells during animal ontogenesis, from early embryo to adult. Recent data show a direct crosstalk between these signaling pathways that seems to be specific for a particular type of neural progenitors. (en)
Title
  • Interaction of Notch and gp130 Signaling in the Maintenance of Neural Stem and Progenitor Cells
  • Interaction of Notch and gp130 Signaling in the Maintenance of Neural Stem and Progenitor Cells (en)
skos:prefLabel
  • Interaction of Notch and gp130 Signaling in the Maintenance of Neural Stem and Progenitor Cells
  • Interaction of Notch and gp130 Signaling in the Maintenance of Neural Stem and Progenitor Cells (en)
skos:notation
  • RIV/00216224:14310/14:00074806!RIV15-MSM-14310___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MSM0021622430)
http://linked.open...iv/cisloPeriodika
  • 1
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
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http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 22293
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14310/14:00074806
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • Neural stem cell; Neural progenitor; Signal transduction; Notch; gp130 (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [0B29C5FE4D8E]
http://linked.open...i/riv/nazevZdroje
  • Cellular and Molecular Neurobiology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 34
http://linked.open...iv/tvurceVysledku
  • Kotasová, Hana
  • Pacherník, Jiří
  • Procházková, Jiřina
http://linked.open...ain/vavai/riv/wos
  • 000330343100001
http://linked.open...n/vavai/riv/zamer
issn
  • 0272-4340
number of pages
http://bibframe.org/vocab/doi
  • 10.1007/s10571-013-9996-6
http://localhost/t...ganizacniJednotka
  • 14310
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