About: Influence of targeted amino acid substitution on specificity and affinity of lectins from pathogenic bacteria

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Influence of targeted amino acid substitution on specificity and affinity of lectins from pathogenic bacteria Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Pseudomonas aeruginosa, Chromobacterium violaceum, Burkholderia cenocepacia and Ralstonia solanacearum are saprophytic bacteria found in various environments, including soil, water and vegetation. The first three bacteria occasionally become aggressive opportunistic animal and human pathogens which attack mainly immunocompromised patients, e.g. patients suffering from cystic fibrosis. The fourth bacterium is economically important plant pathogen. All these bacteria produce lectins. Lectins are proteins which are capable of binding diverse carbohydrates with varying specificity. This fact is very important especially in host-pathogen interactions, where lectins help pathogen in adhesion to sugar moieties presented on host cells. Foregoing bacteria produce lectins belonging to a so-called “PA-IIL family”, namely PA-IIL (P. aeruginosa), CV-IIL (C. violaceum), BC2L-A (B. cenocepacia) and RS-IIL (R. solanacearum). These lectins are orthologues with significant sequential and structural similarities. Pseudomonas aeruginosa, Chromobacterium violaceum, Burkholderia cenocepacia and Ralstonia solanacearum are saprophytic bacteria found in various environments, including soil, water and vegetation. The first three bacteria occasionally become aggressive opportunistic animal and human pathogens which attack mainly immunocompromised patients, e.g. patients suffering from cystic fibrosis. The fourth bacterium is economically important plant pathogen. All these bacteria produce lectins. Lectins are proteins which are capable of binding diverse carbohydrates with varying specificity. This fact is very important especially in host-pathogen interactions, where lectins help pathogen in adhesion to sugar moieties presented on host cells. Foregoing bacteria produce lectins belonging to a so-called “PA-IIL family”, namely PA-IIL (P. aeruginosa), CV-IIL (C. violaceum), BC2L-A (B. cenocepacia) and RS-IIL (R. solanacearum). These lectins are orthologues with significant sequential and structural similarities. (en)
Title	Influence of targeted amino acid substitution on specificity and affinity of lectins from pathogenic bacteria Influence of targeted amino acid substitution on specificity and affinity of lectins from pathogenic bacteria (en)
skos:prefLabel	Influence of targeted amino acid substitution on specificity and affinity of lectins from pathogenic bacteria Influence of targeted amino acid substitution on specificity and affinity of lectins from pathogenic bacteria (en)
skos:notation	RIV/00216224:14310/12:00057922!RIV13-GA0-14310___
http://linked.open...avai/predkladatel	Přírodovědecká fakulta
http://linked.open...avai/riv/aktivita	P S
http://linked.open...avai/riv/aktivity	P(GPP207/11/P185), S
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Dejmková, Eva Pokorná, Martina Malinovská, Lenka Wimmerová, Michaela Mrázková, Jana
http://linked.open.../riv/druhVysledku	O - Ostatní výsledky nezařaditelné do žádného z výše uvedených druhů výsledku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	141598
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/12:00057922
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	lectins; pathogenic bacteria; PA-IIL; Pseudomonas aeruginosa; RS-IIL; Ralstonia solanacearum; BC2L-A; Burkholderia cenocepacia; CV-IIL; Chromobacterium violaceum; site-directed mutagenesis; specificity; affinity; sugar binding (en)
http://linked.open.../riv/klicoveSlovo	lectins affinity Pseudomonas aeruginosa BC2L-A PA-IIL RS-IIL Ralstonia solanacearum pathogenic bacteria Chromobacterium violaceum specificity CV-IIL site-directed mutagenesis sugar binding Burkholderia cenocepacia
http://linked.open...ontrolniKodProRIV	[338F229A5C1C]
http://linked.open...in/vavai/riv/obor	CE
http://linked.open...ichTvurcuVysledku	5 (xsd:int)
http://linked.open...cetTvurcuVysledku	5 (xsd:int)
http://linked.open...vavai/riv/projekt	Preparation of lectins with high specificity and affinity
http://linked.open...UplatneniVysledku	2012
http://linked.open...iv/tvurceVysledku	Dejmková, Eva Malinovská, Lenka Mrázková, Jana Pokorná, Martina Wimmerová, Michaela
http://localhost/t...ganizacniJednotka	14310

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 48 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software