About: Combination of several bioinformatics approaches for the identification of new putative glycosyltransferases in Arabidopsis

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Approximately 450 glycosyltransferase (GT) sequences have been already identified in the Arabidopsis genome that organize into 40 sequence-based families, but a vast majority of these gene products remain biochemically uncharacterized open reading frames. Given the complexity of the cell wall carbohydrate network, it can be inferred that some of the biosynthetic genes have not yet been identified by classical bioinformatics approaches. With the objective to identify new plant GT genes, we designed a bioinformatic strategy that is based on the use of several remote homology detection methods that act at the 1D, 2D, and 3D level. Together, these methods led to the identification of more than 150 candidate protein sequences. Among them, 20 are considered as putative glycosyltransferases that should further be investigated since known GT signatures were clearly identified. Approximately 450 glycosyltransferase (GT) sequences have been already identified in the Arabidopsis genome that organize into 40 sequence-based families, but a vast majority of these gene products remain biochemically uncharacterized open reading frames. Given the complexity of the cell wall carbohydrate network, it can be inferred that some of the biosynthetic genes have not yet been identified by classical bioinformatics approaches. With the objective to identify new plant GT genes, we designed a bioinformatic strategy that is based on the use of several remote homology detection methods that act at the 1D, 2D, and 3D level. Together, these methods led to the identification of more than 150 candidate protein sequences. Among them, 20 are considered as putative glycosyltransferases that should further be investigated since known GT signatures were clearly identified. (en)
Title	Combination of several bioinformatics approaches for the identification of new putative glycosyltransferases in Arabidopsis Combination of several bioinformatics approaches for the identification of new putative glycosyltransferases in Arabidopsis (en)
skos:prefLabel	Combination of several bioinformatics approaches for the identification of new putative glycosyltransferases in Arabidopsis Combination of several bioinformatics approaches for the identification of new putative glycosyltransferases in Arabidopsis (en)
skos:notation	RIV/00216224:14310/09:00036466!RIV10-MSM-14310___
http://linked.open...avai/riv/aktivita	Z
http://linked.open...avai/riv/aktivity	Z(MSM0021622413)
http://linked.open...iv/cisloPeriodika	2
http://linked.open...vai/riv/dodaniDat	2010
http://linked.open...aciTvurceVysledku	Wimmerová, Michaela
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	307529
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/09:00036466
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	fold recognition; glycosyltransferase (en)
http://linked.open.../riv/klicoveSlovo	glycosyltransferase fold recognition
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[E634B496A9C7]
http://linked.open...i/riv/nazevZdroje	Journal of Proteome Research
http://linked.open...in/vavai/riv/obor	BO
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	6 (xsd:int)
http://linked.open...UplatneniVysledku	2009
http://linked.open...v/svazekPeriodika	8
http://linked.open...iv/tvurceVysledku	Imberty, Anne Wimmerová, Michaela Bettler, Emmanuel Breton, Christelle Hansen, Sara Lerouxel, Olivier
http://linked.open...ain/vavai/riv/wos	000263193300035
http://linked.open...n/vavai/riv/zamer	Proteiny v metabolismu a při interakci organismů s prostředím
issn	1535-3893
number of pages	11 (xsd:int)
http://localhost/t...ganizacniJednotka	14310
is http://linked.open...avai/riv/vysledek of	Combination of several bioinformatics approaches for the identification of new putative glycosyltransferases in Arabidopsis Combination of several bioinformatics approaches for the identification of new putative glycosyltransferases in Arabidopsis Combination of several bioinformatics approaches for the identification of new putative glycosyltransferases in Arabidopsis Combination of several bioinformatics approaches for the identification of new putative glycosyltransferases in Arabidopsis

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