About: Polymorphism of DAB genes and variation in parasite species diversity in European populations of chub (Leuciscus cephalus)

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About: Polymorphism of DAB genes and variation in parasite species diversity in European populations of chub (Leuciscus cephalus) Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The polymorphism of major histocompatibility complex (MHC) genes was investigated in relation to parasitism in several populations of chub (Leuciscus cephalus) from different European rivers. The MHC genes are the most polymorphic loci known for vertebrates, whereas tree possible hypotheses of parasite-mediated selection driving an extensive MHC diversity (i.e. overdominance hypothesis, frequency dependent selection hypothesis and hypothesis of optimal number of MHC alleles) have been proposed. Hence, these genes are convenient model for elucidating the host-parasite relationships. It has been predicted that the populations with more genetic variability of MHC will have more diverse array of parasites. The antigens derived from parasites (possible important selective agents) interact with peptide binding region of MHC II molecules, on that account the present study was focused on genetic variability of the exon 2 (DAB1 and DAB3 genes), which encodes the beta 1 domain of the peptide binding region. The polymorphism of major histocompatibility complex (MHC) genes was investigated in relation to parasitism in several populations of chub (Leuciscus cephalus) from different European rivers. The MHC genes are the most polymorphic loci known for vertebrates, whereas tree possible hypotheses of parasite-mediated selection driving an extensive MHC diversity (i.e. overdominance hypothesis, frequency dependent selection hypothesis and hypothesis of optimal number of MHC alleles) have been proposed. Hence, these genes are convenient model for elucidating the host-parasite relationships. It has been predicted that the populations with more genetic variability of MHC will have more diverse array of parasites. The antigens derived from parasites (possible important selective agents) interact with peptide binding region of MHC II molecules, on that account the present study was focused on genetic variability of the exon 2 (DAB1 and DAB3 genes), which encodes the beta 1 domain of the peptide binding region. (en)
Title	Polymorphism of DAB genes and variation in parasite species diversity in European populations of chub (Leuciscus cephalus) Polymorphism of DAB genes and variation in parasite species diversity in European populations of chub (Leuciscus cephalus) (en)
skos:prefLabel	Polymorphism of DAB genes and variation in parasite species diversity in European populations of chub (Leuciscus cephalus) Polymorphism of DAB genes and variation in parasite species diversity in European populations of chub (Leuciscus cephalus) (en)
skos:notation	RIV/00216224:14310/08:00042180!RIV11-MSM-14310___
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(LC522), Z(MSM0021622416)
http://linked.open...vai/riv/dodaniDat	2011
http://linked.open...aciTvurceVysledku	Vetešníková Šimková, Andrea Vyskočilová, Martina Seifertová, Mária
http://linked.open.../riv/druhVysledku	O - Ostatní výsledky nezařaditelné do žádného z výše uvedených druhů výsledku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	387437
http://linked.open...ai/riv/idVysledku	RIV/00216224:14310/08:00042180
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	MHC; parasite; fish (en)
http://linked.open.../riv/klicoveSlovo	MHC fish parasite
http://linked.open...ontrolniKodProRIV	[C12C336EB75D]
http://linked.open...in/vavai/riv/obor	EG
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	3 (xsd:int)
http://linked.open...vavai/riv/projekt	ICHTHYOPASITOLOGY RESEARCH CENTRE
http://linked.open...UplatneniVysledku	2008
http://linked.open...iv/tvurceVysledku	Vetešníková Šimková, Andrea Vyskočilová, Martina Seifertová, Mária
http://linked.open...n/vavai/riv/zamer	Diversity of Biotic Communities and Populations: Causal Analysis of variation in space and time
http://localhost/t...ganizacniJednotka	14310

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