About: Complete Genome Sequence of Treponema paraluiscuniculi, Strain Cuniculi A: The Loss of Infectivity to Humans Is Associated with Genome Decay     Goto   Sponge   NotDistinct   Permalink

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  • Treponema paraluiscuniculi is the causative agent of rabbit venereal spirochetosis. It is not infectious to humans, although its genome structure is very closely related to other pathogenic Treponema species including Treponema pallidum subspecies pallidum, the etiological agent of syphilis. In this study, the genome sequence of Treponema paraluiscuniculi, strain Cuniculi A, was determined by a combination of several high-throughput sequencing strategies. Whereas the overall size (1,133,390 bp), arrangement, and gene content of the Cuniculi A genome closely resembled those of the T. pallidum genome, the T. paraluiscuniculi genome contained a markedly higher number of pseudogenes and gene fragments (51). In addition to pseudogenes, 33 divergent genes were also found in the T. paraluiscuniculi genome. A set of 32 (out of 84) affected genes encoded proteins of known or predicted function in the Nichols genome.
  • Treponema paraluiscuniculi is the causative agent of rabbit venereal spirochetosis. It is not infectious to humans, although its genome structure is very closely related to other pathogenic Treponema species including Treponema pallidum subspecies pallidum, the etiological agent of syphilis. In this study, the genome sequence of Treponema paraluiscuniculi, strain Cuniculi A, was determined by a combination of several high-throughput sequencing strategies. Whereas the overall size (1,133,390 bp), arrangement, and gene content of the Cuniculi A genome closely resembled those of the T. pallidum genome, the T. paraluiscuniculi genome contained a markedly higher number of pseudogenes and gene fragments (51). In addition to pseudogenes, 33 divergent genes were also found in the T. paraluiscuniculi genome. A set of 32 (out of 84) affected genes encoded proteins of known or predicted function in the Nichols genome. (en)
Title
  • Complete Genome Sequence of Treponema paraluiscuniculi, Strain Cuniculi A: The Loss of Infectivity to Humans Is Associated with Genome Decay
  • Complete Genome Sequence of Treponema paraluiscuniculi, Strain Cuniculi A: The Loss of Infectivity to Humans Is Associated with Genome Decay (en)
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  • Complete Genome Sequence of Treponema paraluiscuniculi, Strain Cuniculi A: The Loss of Infectivity to Humans Is Associated with Genome Decay
  • Complete Genome Sequence of Treponema paraluiscuniculi, Strain Cuniculi A: The Loss of Infectivity to Humans Is Associated with Genome Decay (en)
skos:notation
  • RIV/00216224:14110/11:00049952!RIV12-GA0-14110___
http://linked.open...avai/predkladatel
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  • P(GA310/07/0321)
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  • 5
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  • 191377
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  • RIV/00216224:14110/11:00049952
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  • ZEALAND WHITE-RABBITS; PALLIDUM SSP-PALLIDUM; REPEAT PROTEIN ARP; ESCHERICHIA-COLI; SYPHILIS SPIROCHETE; MULTIPLE ALLELES; GENE CONVERSION; TPRK GENE; IDENTIFICATION; EXPRESSION (en)
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  • US - Spojené státy americké
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  • [ADBE8AB29652]
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  • Plos One
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  • 6
http://linked.open...iv/tvurceVysledku
  • Albert, Tom
  • Buhay, Christian
  • Chen, Lei
  • Dugan-Rocha, Shannon
  • Gibbs, Richard A.
  • Hallsworth-Pepin, Kym
  • Muzny, Donna M.
  • Norris, Steven J.
  • Pospíšilová, Petra
  • Qin, Xiang
  • Strouhal, Michal
  • Weinstock, George M.
  • Zobaníková, Marie
  • Čejková, Darina
  • Šmajs, David
http://linked.open...ain/vavai/riv/wos
  • 000291097600063
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  • 1932-6203
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  • 10.1371/journal.pone.0020415
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  • 14110
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