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  • V review jsou shrnuty vlastní a publikované výsledky naznačující vliv Schwannových buněk a endoneuriální extracelulární matrix na sortování regenerujících axonů v periferních nervech. (cs)
  • Besides very well elaborated microsurgical management of severed peripheral nerves, the clinical results of functional recovery following surgical repair of mixed nerves are disappointing. An improvement of functional recovery after peripheral nerve lesion requires the accurate regeneration of axons to their original target tissues and structures. Therefore, better clinical results could be obtained by a greater understanding of the cellular and molecular biology of selective nerve regeneration. The studies concerning Schwann cells and their endoneurial extracellular matrix as potent cues for selective promotion and influence of regenerating motor and sensory axons are reviewed. Knowledge of the sorting mechanisms of regenerated motor and sensory axons is needed not only for improvement of functional recovery, but also for the development of biocompatible nerve prostheses.
  • Besides very well elaborated microsurgical management of severed peripheral nerves, the clinical results of functional recovery following surgical repair of mixed nerves are disappointing. An improvement of functional recovery after peripheral nerve lesion requires the accurate regeneration of axons to their original target tissues and structures. Therefore, better clinical results could be obtained by a greater understanding of the cellular and molecular biology of selective nerve regeneration. The studies concerning Schwann cells and their endoneurial extracellular matrix as potent cues for selective promotion and influence of regenerating motor and sensory axons are reviewed. Knowledge of the sorting mechanisms of regenerated motor and sensory axons is needed not only for improvement of functional recovery, but also for the development of biocompatible nerve prostheses. (en)
Title
  • Schwann cells and endoneurial extracellular matrix molecules as potential cues for sorting of regenerated axons: A review
  • Schwann cells and endoneurial extracellular matrix molecules as potential cues for sorting of regenerated axons: A review (en)
  • Schwannovy buňky a endoneuriální extracelulární matrix a jejich vliv na sortování regenerovaných axonů (cs)
skos:prefLabel
  • Schwann cells and endoneurial extracellular matrix molecules as potential cues for sorting of regenerated axons: A review
  • Schwann cells and endoneurial extracellular matrix molecules as potential cues for sorting of regenerated axons: A review (en)
  • Schwannovy buňky a endoneuriální extracelulární matrix a jejich vliv na sortování regenerovaných axonů (cs)
skos:notation
  • RIV/00216224:14110/04:00010572!RIV09-GA0-14110___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA309/00/0407), Z(MSM 141100001)
http://linked.open...iv/cisloPeriodika
  • 2
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 585555
http://linked.open...ai/riv/idVysledku
  • RIV/00216224:14110/04:00010572
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • nerve regeneration; selective reinnervation; sensory and motor axons (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • JP - Japonsko
http://linked.open...ontrolniKodProRIV
  • [8F567D8A00E6]
http://linked.open...i/riv/nazevZdroje
  • Anatomical Science International
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 79
http://linked.open...iv/tvurceVysledku
  • Dubový, Petr
http://linked.open...n/vavai/riv/zamer
issn
  • 1447-6959
number of pages
http://localhost/t...ganizacniJednotka
  • 14110
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