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rdf:type
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Description
| - The dorsal and ventral spinal roots contain a dominant amount of afferent and motor axons, respectively. Besides differences of intrinsic capacities of the motor and primary sensory neurons for axon regeneration, we hypothesize different cellular and extracellular conditions in the dorsal and ventral roots based on various types of axons. Chondroitin sulfate proteoglycan (CSPG), fibronectin (FN), tenascin (TN) and thrombospondin (TSP) as well as BDNF, NGF and NT-3 were investigated by optimized indirect immunofluorescence method. Intensity of immunofluorescence staining was compared using the computer-assisted image analysis. The measurement of immunofluorescence intensity revealed that the endoneurial ECM of the dorsal roots was immunostained for the studied molecules at a higher intensity than in the ventral roots. Two weeks after root transection, the immunofluorescence intensity for ECM molecules decreased in comparison to intact roots. In addition, a higher intensity for CSPG remained in the dors
- The dorsal and ventral spinal roots contain a dominant amount of afferent and motor axons, respectively. Besides differences of intrinsic capacities of the motor and primary sensory neurons for axon regeneration, we hypothesize different cellular and extracellular conditions in the dorsal and ventral roots based on various types of axons. Chondroitin sulfate proteoglycan (CSPG), fibronectin (FN), tenascin (TN) and thrombospondin (TSP) as well as BDNF, NGF and NT-3 were investigated by optimized indirect immunofluorescence method. Intensity of immunofluorescence staining was compared using the computer-assisted image analysis. The measurement of immunofluorescence intensity revealed that the endoneurial ECM of the dorsal roots was immunostained for the studied molecules at a higher intensity than in the ventral roots. Two weeks after root transection, the immunofluorescence intensity for ECM molecules decreased in comparison to intact roots. In addition, a higher intensity for CSPG remained in the dors (en)
- Dorsální a ventrální kořeny spinálních nervů obsahují aferentní a eferentní nervová vlákna, kolem kterých je vytvořena ECM rozdílného molekulárního složení. (cs)
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Title
| - A QUANTITATIVE IMMUNOFLUORESCENCE ANALYSIS OF SOME ECM MOLECULES AND NEUROTROPHINS ALONGSIDE AFFERENT AND MOTOR AXONS IN THE DORSAL AND VENTRAL SPINAL ROOTS
- A QUANTITATIVE IMMUNOFLUORESCENCE ANALYSIS OF SOME ECM MOLECULES AND NEUROTROPHINS ALONGSIDE AFFERENT AND MOTOR AXONS IN THE DORSAL AND VENTRAL SPINAL ROOTS (en)
- Kvantitativní imunofluorescenční analýza ECM molekul (cs)
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skos:prefLabel
| - A QUANTITATIVE IMMUNOFLUORESCENCE ANALYSIS OF SOME ECM MOLECULES AND NEUROTROPHINS ALONGSIDE AFFERENT AND MOTOR AXONS IN THE DORSAL AND VENTRAL SPINAL ROOTS
- A QUANTITATIVE IMMUNOFLUORESCENCE ANALYSIS OF SOME ECM MOLECULES AND NEUROTROPHINS ALONGSIDE AFFERENT AND MOTOR AXONS IN THE DORSAL AND VENTRAL SPINAL ROOTS (en)
- Kvantitativní imunofluorescenční analýza ECM molekul (cs)
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skos:notation
| - RIV/00216224:14110/02:00005820!RIV09-GA0-14110___
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http://linked.open...avai/riv/aktivita
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http://linked.open...avai/riv/aktivity
| - P(GA309/00/0407), Z(MSM 141100001)
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http://linked.open...iv/cisloPeriodika
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http://linked.open...vai/riv/dodaniDat
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http://linked.open...aciTvurceVysledku
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http://linked.open.../riv/druhVysledku
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http://linked.open...iv/duvernostUdaju
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http://linked.open...titaPredkladatele
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http://linked.open...dnocenehoVysledku
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http://linked.open...ai/riv/idVysledku
| - RIV/00216224:14110/02:00005820
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http://linked.open...riv/jazykVysledku
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http://linked.open.../riv/klicovaSlova
| - endoneurium; extracellular; matrix; neurotrophins (en)
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http://linked.open.../riv/klicoveSlovo
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http://linked.open...odStatuVydavatele
| - US - Spojené státy americké
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http://linked.open...ontrolniKodProRIV
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http://linked.open...i/riv/nazevZdroje
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http://linked.open...in/vavai/riv/obor
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http://linked.open...ichTvurcuVysledku
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
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http://linked.open...UplatneniVysledku
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http://linked.open...v/svazekPeriodika
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http://linked.open...iv/tvurceVysledku
| - Dubový, Petr
- Hradilová Svíženská, Ivana
- Klusáková, Ilona
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http://linked.open...ain/vavai/riv/wos
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http://linked.open...n/vavai/riv/zamer
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issn
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number of pages
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http://localhost/t...ganizacniJednotka
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