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  • The basal laminae of the peripheral nervous system are produced by Schwann and perineurial cells. Laminins, predominant glycoproteins of the basal laminae, play a role in adherence, growth, morphology, migration, and differentiation of the cells. There is conclusive evidence that laminin molecules promote the axon outgrowth and migration of Schwann cells. Laminins are heterotrimers composed of a,b and g chains that combine to form at least 11 isoforms. It is assumed that different compartments of the peripheral nervous system exhibit different laminin isoforms. Therefore, we have localised a distribution of laminin-1, -2, and -3 isoforms and some individual laminin chains (a1,b2,b3,g2) in the rat femoral nerve and Pacinian corpuscles by indirect immunofluorescence technique. In addition, location of laminin-1,-2, and -3 isoforms were studied in Pacinian corpuscles by immunogold electron microscopic technique. The results of immunohistochemical and immunogold detection of laminins confirmed that differ
  • The basal laminae of the peripheral nervous system are produced by Schwann and perineurial cells. Laminins, predominant glycoproteins of the basal laminae, play a role in adherence, growth, morphology, migration, and differentiation of the cells. There is conclusive evidence that laminin molecules promote the axon outgrowth and migration of Schwann cells. Laminins are heterotrimers composed of a,b and g chains that combine to form at least 11 isoforms. It is assumed that different compartments of the peripheral nervous system exhibit different laminin isoforms. Therefore, we have localised a distribution of laminin-1, -2, and -3 isoforms and some individual laminin chains (a1,b2,b3,g2) in the rat femoral nerve and Pacinian corpuscles by indirect immunofluorescence technique. In addition, location of laminin-1,-2, and -3 isoforms were studied in Pacinian corpuscles by immunogold electron microscopic technique. The results of immunohistochemical and immunogold detection of laminins confirmed that differ (en)
Title
  • Immunohistochemical and immunogold analysis of laminins in the peripheral nerve structures
  • Immunohistochemical and immunogold analysis of laminins in the peripheral nerve structures (en)
skos:prefLabel
  • Immunohistochemical and immunogold analysis of laminins in the peripheral nerve structures
  • Immunohistochemical and immunogold analysis of laminins in the peripheral nerve structures (en)
skos:notation
  • RIV/00216224:14110/01:00004875!RIV/2002/GA0/141102/N
http://linked.open.../vavai/riv/strany
  • 233
http://linked.open...avai/riv/aktivita
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  • P(GA309/00/0407), Z(MSM 141100001)
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  • 4
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  • 682410
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  • RIV/00216224:14110/01:00004875
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  • Immunohistochemical and immunogold analysis of laminins in the peripheral nerve structures (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • NL - Nizozemsko
http://linked.open...ontrolniKodProRIV
  • [C9B7381EECE5]
http://linked.open...i/riv/nazevZdroje
  • The Histochemical Journal
http://linked.open...in/vavai/riv/obor
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http://linked.open...cetTvurcuVysledku
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http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 33
http://linked.open...iv/tvurceVysledku
  • Dubový, Petr
  • Klusáková, Ilona
  • Ghalib, Nabil Ahmed
  • Svíženská, Ivana
http://linked.open...n/vavai/riv/zamer
issn
  • 0018-2214
number of pages
http://localhost/t...ganizacniJednotka
  • 14110
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