About: Immunohistochemical differences in the ECM content alongside afferent and motor axons in relation to the position of the dorsal root ganglion

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About: Immunohistochemical differences in the ECM content alongside afferent and motor axons in relation to the position of the dorsal root ganglion Goto Sponge NotDistinct Permalink

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	The extracellular matrix (ECM) provides signalling cues that regulate cell behaviour during peripheral nerve formation and homeostasis. Composition of the ECM is the major determinant of the microenvironmental condition that controls the nerve regeneration. To reveal different microenvironmental conditions for motor and afferent axons we have analysed immunohistochemically some ECM components and adhesion molecules (laminin-2, -3, fibronectin, thrombospondin, tenascin, chondroitin sulphate, and HNK-1) in the spinal roots and branches of the spinal nerve. The results of quantitative immunofluorescence analysis suggest some differences in the content of ECM along the afferent and motor axons that could be involved in the origin of different conditions for the axon regrowth after injury of the dorsal and ventral roots as well as the spinal nerves. The extracellular matrix (ECM) provides signalling cues that regulate cell behaviour during peripheral nerve formation and homeostasis. Composition of the ECM is the major determinant of the microenvironmental condition that controls the nerve regeneration. To reveal different microenvironmental conditions for motor and afferent axons we have analysed immunohistochemically some ECM components and adhesion molecules (laminin-2, -3, fibronectin, thrombospondin, tenascin, chondroitin sulphate, and HNK-1) in the spinal roots and branches of the spinal nerve. The results of quantitative immunofluorescence analysis suggest some differences in the content of ECM along the afferent and motor axons that could be involved in the origin of different conditions for the axon regrowth after injury of the dorsal and ventral roots as well as the spinal nerves. (en)
Title	Immunohistochemical differences in the ECM content alongside afferent and motor axons in relation to the position of the dorsal root ganglion Immunohistochemical differences in the ECM content alongside afferent and motor axons in relation to the position of the dorsal root ganglion (en)
skos:prefLabel	Immunohistochemical differences in the ECM content alongside afferent and motor axons in relation to the position of the dorsal root ganglion Immunohistochemical differences in the ECM content alongside afferent and motor axons in relation to the position of the dorsal root ganglion (en)
skos:notation	RIV/00216224:14110/01:00004871!RIV/2002/GA0/141102/N
http://linked.open.../vavai/riv/strany	247
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(GA309/00/0407), Z(MSM 141100001)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2002
http://linked.open...aciTvurceVysledku	Hradilová Svíženská, Ivana Ghalib, Nabil Ahmed Dubový, Petr Klusáková, Ilona
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Masarykova univerzita / Lékařská fakulta
http://linked.open...dnocenehoVysledku	682411
http://linked.open...ai/riv/idVysledku	RIV/00216224:14110/01:00004871
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Immunohistochemical differences in the ECM content alongside afferent and motor axons in relation to the position of the dorsal root ganglion (en)
http://linked.open.../riv/klicoveSlovo	Immunohistochemical differences in the ECM content alongside afferent and motor axons in relation to the position of the dorsal root ganglion
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[0EAD0DBCE1DF]
http://linked.open...i/riv/nazevZdroje	The Histochemical Journal
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	4 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...ocetUcastnikuAkce	0 (xsd:int)
http://linked.open...nichUcastnikuAkce	0 (xsd:int)
http://linked.open...vavai/riv/projekt	Cellular and extracellular environment for the axon regeneration following injury of the spinal roots and peripheral nerves
http://linked.open...UplatneniVysledku	2001
http://linked.open...v/svazekPeriodika	33
http://linked.open...iv/tvurceVysledku	Dubový, Petr Klusáková, Ilona Ghalib, Nabil Ahmed Svíženská, Ivana
http://linked.open...n/vavai/riv/zamer	http://linked.opendata.cz/resource/domain/vavai/zamer/MSM%20141100001
issn	0018-2214
number of pages	2 (xsd:int)
http://localhost/t...ganizacniJednotka	14110

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