About: Human adaptations to diet, subsistence and ecoregion are due to subtle shifts in allele frequency     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
Description
  • Human populations use a variety of subsistence strategies to exploit an exceptionally broad range of ecoregions and dietary components. These aspects of human environments have changed dramatically during human evolution, giving rise to new selective pressures. We combine population genetics data with ecological information to detect variants that increased in frequency in response to new selective pressures. Our approach detects SNPs that show concordant differences in allele frequencies across populations with respect to specific aspects of the environment. Genic and especially nonsynonymous SNPs are overrepresented among those most strongly correlated with environmental variables. This provides genome-wide evidence for selection due to changes in ecoregion, diet, and subsistence. We find particularly strong signals associated with polar ecoregions, with foraging, and with a diet rich in roots and tubers.
  • Human populations use a variety of subsistence strategies to exploit an exceptionally broad range of ecoregions and dietary components. These aspects of human environments have changed dramatically during human evolution, giving rise to new selective pressures. We combine population genetics data with ecological information to detect variants that increased in frequency in response to new selective pressures. Our approach detects SNPs that show concordant differences in allele frequencies across populations with respect to specific aspects of the environment. Genic and especially nonsynonymous SNPs are overrepresented among those most strongly correlated with environmental variables. This provides genome-wide evidence for selection due to changes in ecoregion, diet, and subsistence. We find particularly strong signals associated with polar ecoregions, with foraging, and with a diet rich in roots and tubers. (en)
Title
  • Human adaptations to diet, subsistence and ecoregion are due to subtle shifts in allele frequency
  • Human adaptations to diet, subsistence and ecoregion are due to subtle shifts in allele frequency (en)
skos:prefLabel
  • Human adaptations to diet, subsistence and ecoregion are due to subtle shifts in allele frequency
  • Human adaptations to diet, subsistence and ecoregion are due to subtle shifts in allele frequency (en)
skos:notation
  • RIV/00216208:11410/10:10080356!RIV11-MSM-11410___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • Z(MSM0021620828), Z(MSM0021620843)
http://linked.open...iv/cisloPeriodika
  • 2
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 262317
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11410/10:10080356
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • genome-wide association studies; foraging; cold tolerance (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [32A3D6B06AFF]
http://linked.open...i/riv/nazevZdroje
  • Proceedings of the National Academy of Sciences of the United States of America
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 107
http://linked.open...iv/tvurceVysledku
  • Ehler, Edvard
  • Coop, Graham
  • Alkorta-Aranburu, Gorka
  • Beall, Cynthia
  • Di Rienzo, Anna
  • Gebremedhin, Amha
  • Hancock, Angela M.
  • Pritchard, Jonathan
  • Sukernik, Rem
  • Utermann, Gerd
  • Witonsky, David B.
http://linked.open...ain/vavai/riv/wos
  • 000277553800005
http://linked.open...n/vavai/riv/zamer
issn
  • 0027-8424
number of pages
http://localhost/t...ganizacniJednotka
  • 11410
is http://linked.open...avai/riv/vysledek of
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 58 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software