About: Electrochemical DNA Biosensors - Useful Diagnostic Tools for the Detection of Damage to DNA Caused by Organic Xenobiotics (A Review)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
Description	Supramolecular interactions of various organic xenobiotic compounds with DNA are among the most important aspects of biological studies in clinical analysis, drug discovery, and pharmaceutical development processes. In recent years, there has been a growing interest in the electrochemical investigation of interactions between studied analytes and DNA. Observing the pre- and post-electrochemical signals of DNA or monitoring its interaction with xenobiotics provides good evidence for the interaction mechanism to be elucidated. Such interaction can also be used for sensitive determination of these compounds. This short review should provide evidence that the electrochemical approach brings new insight into human health protection or rational drug design and leads to further understanding of the interaction mechanism between organic xenobiotic compounds and DNA. Supramolecular interactions of various organic xenobiotic compounds with DNA are among the most important aspects of biological studies in clinical analysis, drug discovery, and pharmaceutical development processes. In recent years, there has been a growing interest in the electrochemical investigation of interactions between studied analytes and DNA. Observing the pre- and post-electrochemical signals of DNA or monitoring its interaction with xenobiotics provides good evidence for the interaction mechanism to be elucidated. Such interaction can also be used for sensitive determination of these compounds. This short review should provide evidence that the electrochemical approach brings new insight into human health protection or rational drug design and leads to further understanding of the interaction mechanism between organic xenobiotic compounds and DNA. (en)
Title	Electrochemical DNA Biosensors - Useful Diagnostic Tools for the Detection of Damage to DNA Caused by Organic Xenobiotics (A Review) Electrochemical DNA Biosensors - Useful Diagnostic Tools for the Detection of Damage to DNA Caused by Organic Xenobiotics (A Review) (en)
skos:prefLabel	Electrochemical DNA Biosensors - Useful Diagnostic Tools for the Detection of Damage to DNA Caused by Organic Xenobiotics (A Review) Electrochemical DNA Biosensors - Useful Diagnostic Tools for the Detection of Damage to DNA Caused by Organic Xenobiotics (A Review) (en)
skos:notation	RIV/00216208:11310/12:10126423!RIV13-GA0-11310___
http://linked.open...avai/predkladatel	Přírodovědecká fakulta
http://linked.open...avai/riv/aktivita	P S Z
http://linked.open...avai/riv/aktivity	P(GBP206/12/G151), P(ME10004), S, Z(MSM0021620857)
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Vyskočil, Vlastimil Hájková, Andrea Krejčová, Zuzana Blašková, Marta Stávková, Klára Horáková, Eva
http://linked.open.../riv/druhVysledku	O - Ostatní výsledky nezařaditelné do žádného z výše uvedených druhů výsledku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / Přírodovědecká fakulta
http://linked.open...dnocenehoVysledku	133867
http://linked.open...ai/riv/idVysledku	RIV/00216208:11310/12:10126423
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Review.; DNA damage detection; DNA biosensors; Supramolecular chemistry (en)
http://linked.open.../riv/klicoveSlovo	DNA biosensors DNA damage detection Review. Supramolecular chemistry
http://linked.open...ontrolniKodProRIV	[0D4070D42138]
http://linked.open...in/vavai/riv/obor	CG
http://linked.open...ichTvurcuVysledku	6 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	Center of novel approaches to bioanalysis and molecular diagnostics New electrode materials for voltammetric and amperometric detection of trace amounts of ecotoxic and genotoxic organic pollutants
http://linked.open...UplatneniVysledku	2012
http://linked.open...iv/tvurceVysledku	Hájková, Andrea Vyskočil, Vlastimil Wang, Joseph Blašková, Marta Horáková, Eva Krejčová, Zuzana Stávková, Klára
http://linked.open...n/vavai/riv/zamer	Nové molekulární systémy pro pokročilé aplikace prospěšné pro zdraví a šetrné k životnímu prostředí
http://localhost/t...ganizacniJednotka	11310

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