About: Antiarrhythmic effect of prolonged morphine exposure is accompanied by altered myocardial adenylyl cyclase signaling in rats     Goto   Sponge   NotDistinct   Permalink

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  • We have studied the effect of sustained administration of morphine in high doses on myocardial adenylyl cyclase signaling and cardiac ischemic tolerance. Our results indicated that prolonged treatment of morphine substantially alters the function of myocardial G-protein-regulated adenylyl cyclase signaling and reduced susceptibility to ischemia-induced ventricular arrhythmias.
  • We have studied the effect of sustained administration of morphine in high doses on myocardial adenylyl cyclase signaling and cardiac ischemic tolerance. Our results indicated that prolonged treatment of morphine substantially alters the function of myocardial G-protein-regulated adenylyl cyclase signaling and reduced susceptibility to ischemia-induced ventricular arrhythmias. (en)
Title
  • Antiarrhythmic effect of prolonged morphine exposure is accompanied by altered myocardial adenylyl cyclase signaling in rats
  • Antiarrhythmic effect of prolonged morphine exposure is accompanied by altered myocardial adenylyl cyclase signaling in rats (en)
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  • Antiarrhythmic effect of prolonged morphine exposure is accompanied by altered myocardial adenylyl cyclase signaling in rats
  • Antiarrhythmic effect of prolonged morphine exposure is accompanied by altered myocardial adenylyl cyclase signaling in rats (en)
skos:notation
  • RIV/00216208:11310/12:10123865!RIV13-AV0-11310___
http://linked.open...avai/predkladatel
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  • P(IAA501110901), S, Z(AV0Z50110509), Z(MSM0021620858)
http://linked.open...iv/cisloPeriodika
  • 2
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  • 122881
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  • RIV/00216208:11310/12:10123865
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  • arrhythmias; G-proteins; adenylyl cyclase; morphine; rat myocardium (en)
http://linked.open.../riv/klicoveSlovo
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  • PL - Polská republika
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  • [0A4C12EE2D7A]
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  • Pharmacological Reports
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  • 64
http://linked.open...iv/tvurceVysledku
  • Neckář, Jan
  • Novotný, Jiří
  • Kolář, František
  • Bartoňová, Iveta
  • Hejnová, Lucie
  • Škrabalová, Jitka
http://linked.open...ain/vavai/riv/wos
  • 000305546700014
http://linked.open...n/vavai/riv/zamer
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  • 1734-1140
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  • 11310
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