About: Histone deacetylase inhibitors valproate and trichostatin A are toxic to neuroblastoma cells and modulate cytochrome P450 1A1, 1B1 and 3A4 expression in these cells     Goto   Sponge   NotDistinct   Permalink

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Description
  • The cytotoxic effect of valproic acid and trichostatin A to human neuroblastoma UKF-NB-3, UKF-NB-4 and SK-N-AS cancer cell lines was investigated in this study. These HDCA inhibitors are cytotoxic to neuroblastomas and induce CYP 1A1 and 3A4 in some of these cells.
  • The cytotoxic effect of valproic acid and trichostatin A to human neuroblastoma UKF-NB-3, UKF-NB-4 and SK-N-AS cancer cell lines was investigated in this study. These HDCA inhibitors are cytotoxic to neuroblastomas and induce CYP 1A1 and 3A4 in some of these cells. (en)
Title
  • Histone deacetylase inhibitors valproate and trichostatin A are toxic to neuroblastoma cells and modulate cytochrome P450 1A1, 1B1 and 3A4 expression in these cells
  • Histone deacetylase inhibitors valproate and trichostatin A are toxic to neuroblastoma cells and modulate cytochrome P450 1A1, 1B1 and 3A4 expression in these cells (en)
skos:prefLabel
  • Histone deacetylase inhibitors valproate and trichostatin A are toxic to neuroblastoma cells and modulate cytochrome P450 1A1, 1B1 and 3A4 expression in these cells
  • Histone deacetylase inhibitors valproate and trichostatin A are toxic to neuroblastoma cells and modulate cytochrome P450 1A1, 1B1 and 3A4 expression in these cells (en)
skos:notation
  • RIV/00216208:11310/09:10001351!RIV11-MZ0-11310___
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • I, P(NR9522), Z(MSM0021620813)
http://linked.open...iv/cisloPeriodika
  • 3
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 317215
http://linked.open...ai/riv/idVysledku
  • RIV/00216208:11310/09:10001351
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • expression; 3A4; 1B1; cytochrome P450 1A1; neuroblastoma cells; toxic; trichostatin A; valproate; Histone deacetylase inhibitors (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • SK - Slovenská republika
http://linked.open...ontrolniKodProRIV
  • [D5838C62D8F9]
http://linked.open...i/riv/nazevZdroje
  • Interdisciplinary Toxicology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 2
http://linked.open...iv/tvurceVysledku
  • Eckschlager, Tomáš
  • Hraběta, Jan
  • Procházka, Pavel
  • Poljaková, Jitka
  • Stiborová, Marie
  • Smutný, Svatopluk
  • Hřebačková, Jana
http://linked.open...n/vavai/riv/zamer
issn
  • 1337-6853
number of pages
http://localhost/t...ganizacniJednotka
  • 11310
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