About: Increased adiponectin is negatively linked to the local inflammatory process in patients with rheumatoid arthritis

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About: Increased adiponectin is negatively linked to the local inflammatory process in patients with rheumatoid arthritis Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://dx.doi.org/10.1016/j.cyto.2006.09.002
Description	Adiponectin has been shown to exert insulin-sensitizing, anti-atherogenic, and anti-inflammatory properties in metabolic diseases. It has been suggested that adiponectin may play a role in rheumatoid arthritis (RA). To assess adiponectin in serum and synovial fluid from patients with RA and osteoarthritis (OA), and in serum from healthy controls. Adiponectin and CRP levels were analyzed by ELISA. The clinical activity of RA patients was assessed according to the 28 joint count Disease Activity Score. Synovial fluid adiponectin was significantly higher in RA than in OA patients (p < 0.001). Adiponectin was negatively associated with the leukocyte count in RA synovial fluid (r = -0.45, p < 0.05). Serum adiponectin was higher in RA compared to healthy controls) < 0.02), however comparable to OA patients. Serum adiponectin was higher than in synovial fluid in both diseases (p < 0.001). In general, women had higher adiponectin levels than men. Adiponectin was not related to age, disease duratio Adiponectin has been shown to exert insulin-sensitizing, anti-atherogenic, and anti-inflammatory properties in metabolic diseases. It has been suggested that adiponectin may play a role in rheumatoid arthritis (RA). To assess adiponectin in serum and synovial fluid from patients with RA and osteoarthritis (OA), and in serum from healthy controls. Adiponectin and CRP levels were analyzed by ELISA. The clinical activity of RA patients was assessed according to the 28 joint count Disease Activity Score. Synovial fluid adiponectin was significantly higher in RA than in OA patients (p < 0.001). Adiponectin was negatively associated with the leukocyte count in RA synovial fluid (r = -0.45, p < 0.05). Serum adiponectin was higher in RA compared to healthy controls) < 0.02), however comparable to OA patients. Serum adiponectin was higher than in synovial fluid in both diseases (p < 0.001). In general, women had higher adiponectin levels than men. Adiponectin was not related to age, disease duratio (en)
Title	Increased adiponectin is negatively linked to the local inflammatory process in patients with rheumatoid arthritis Increased adiponectin is negatively linked to the local inflammatory process in patients with rheumatoid arthritis (en)
skos:prefLabel	Increased adiponectin is negatively linked to the local inflammatory process in patients with rheumatoid arthritis Increased adiponectin is negatively linked to the local inflammatory process in patients with rheumatoid arthritis (en)
skos:notation	RIV/00216208:11120/06:00003043!RIV12-MSM-11120___
http://linked.open...avai/riv/aktivita	I Z
http://linked.open...avai/riv/aktivity	I, Z(MZ0RU2005)
http://linked.open...iv/cisloPeriodika	5-6
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Housa, Daniel
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 3. lékařská fakulta
http://linked.open...dnocenehoVysledku	479182
http://linked.open...ai/riv/idVysledku	RIV/00216208:11120/06:00003043
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	adiponectin; rheumatoid arthritis; osteoarthritis (en)
http://linked.open.../riv/klicoveSlovo	osteoarthritis adiponectin rheumatoid arthritis
http://linked.open...odStatuVydavatele	GB - Spojené království Velké Británie a Severního Irska
http://linked.open...ontrolniKodProRIV	[A49A401D5ED0]
http://linked.open...i/riv/nazevZdroje	Cytokine
http://linked.open...in/vavai/riv/obor	FB
http://linked.open...ichTvurcuVysledku	1 (xsd:int)
http://linked.open...cetTvurcuVysledku	4 (xsd:int)
http://linked.open...UplatneniVysledku	2006
http://linked.open...v/svazekPeriodika	35
http://linked.open...iv/tvurceVysledku	Šenolt, L. Housa, Daniel
http://linked.open...ain/vavai/riv/wos	000243154800004
http://linked.open...n/vavai/riv/zamer	Etiopatogenetické mechanizmy, molekulárně genetické základy, sociálně zdravotní důsledky a terapie, refrakterních forem, zánětlivých i nezánětlivých revmatických onemocnění
issn	1043-4666
number of pages	6 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.cyto.2006.09.002
http://localhost/t...ganizacniJednotka	11120

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