About: HLA DRB1*1501 is only modestly associated with lesion burden at the first demyelinating event

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About: HLA DRB1*1501 is only modestly associated with lesion burden at the first demyelinating event Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Vysledek, within Data Space : linked.opendata.cz associated with source document(s)

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rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://dx.doi.org/10.1016/j.jneuroim.2011.04.011
Description	The objectives were to assess the associations between HLA DRB11501 status and magnetic resonance imaging (MRI) measures in clinically isolated syndromes (CIS) at the first demyelinating event. Methods: We genotyped 205 CIS patients (age: 29.0 +/- 7.7 years) enrolled in the Observational Study of Early Interferon beta 1-a Treatment in High Risk Subjects after CIS (SET study), a multi-center, clinical study of CIS for rs3135005, a single nucleotide polymorphism associated with HLA DRB11501 status. The inclusion criteria required 2 or more brain MRI lesions and the presence of two or more oligoclonal bands in cerebrospinal fluid. The objectives were to assess the associations between HLA DRB11501 status and magnetic resonance imaging (MRI) measures in clinically isolated syndromes (CIS) at the first demyelinating event. Methods: We genotyped 205 CIS patients (age: 29.0 +/- 7.7 years) enrolled in the Observational Study of Early Interferon beta 1-a Treatment in High Risk Subjects after CIS (SET study), a multi-center, clinical study of CIS for rs3135005, a single nucleotide polymorphism associated with HLA DRB11501 status. The inclusion criteria required 2 or more brain MRI lesions and the presence of two or more oligoclonal bands in cerebrospinal fluid. (en)
Title	HLA DRB11501 is only modestly associated with lesion burden at the first demyelinating event HLA DRB11501 is only modestly associated with lesion burden at the first demyelinating event (en)
skos:prefLabel	HLA DRB11501 is only modestly associated with lesion burden at the first demyelinating event HLA DRB11501 is only modestly associated with lesion burden at the first demyelinating event (en)
skos:notation	RIV/00216208:11110/11:8891!RIV12-MZ0-11110___
http://linked.open...avai/predkladatel	1. lékařská fakulta
http://linked.open...avai/riv/aktivita	P Z
http://linked.open...avai/riv/aktivity	P(1A8713), Z(MSM0021620849)
http://linked.open...iv/cisloPeriodika	1-2
http://linked.open...vai/riv/dodaniDat	2012
http://linked.open...aciTvurceVysledku	Vaněčková, Manuela Seidl, Zdeněk Havrdová, Eva Týblová, Michaela Krásenský, Jan Horáková, Dana Lelková, Petra
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Univerzita Karlova v Praze / 1. lékařská fakulta
http://linked.open...dnocenehoVysledku	202268
http://linked.open...ai/riv/idVysledku	RIV/00216208:11110/11:8891
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	Multiple sclerosis; HLA; Genetics; Clinically isolated syndromes; Progression; MRI; clinically isolated syndromes; multiple-sclerosis; optic neuritis; follow-up; brain atrophy; mri; ms; risk; susceptibility; pathogenesis (en)
http://linked.open.../riv/klicoveSlovo	Genetics MRI follow-up pathogenesis risk susceptibility Clinically isolated syndromes HLA Multiple sclerosis Progression brain atrophy clinically isolated syndromes mri ms multiple-sclerosis optic neuritis
http://linked.open...odStatuVydavatele	NL - Nizozemsko
http://linked.open...ontrolniKodProRIV	[2478AEB910AA]
http://linked.open...i/riv/nazevZdroje	Journal of Neuroimmunology
http://linked.open...in/vavai/riv/obor	FH
http://linked.open...ichTvurcuVysledku	7 (xsd:int)
http://linked.open...cetTvurcuVysledku	14 (xsd:int)
http://linked.open...vavai/riv/projekt	Pharmacogenomics - a promising way for reasonable and efficacious multiple sclerosis treatment
http://linked.open...UplatneniVysledku	2011
http://linked.open...v/svazekPeriodika	236
http://linked.open...iv/tvurceVysledku	Havrdová, Eva Seidl, Zdeněk Vaněčková, Manuela Bergsland, Niels Horáková, Dana Hussein, Sara Krásenský, Jan Lelková, Petra Ramanathan, M. Tamano-Blanco, Miriam Týblová, Michaela Weinstock-Guttman, B. Willis, Laura Zivadinov, Robert
http://linked.open...ain/vavai/riv/wos	000293490900010
http://linked.open...n/vavai/riv/zamer	Neuropsychiatrické aspekty neurodegenerativních onemocnění
issn	0165-5728
number of pages	5 (xsd:int)
http://localhost/t...ganizacniJednotka	11110
is http://linked.open...avai/riv/vysledek of	HLA DRB11501 is only modestly associated with lesion burden at the first demyelinating event HLA DRB11501 is only modestly associated with lesion burden at the first demyelinating event

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