About: The impact of the microbial load of genital mycoplasmas and gestational age on the intensity of intraamniotic inflammation

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About: The impact of the microbial load of genital mycoplasmas and gestational age on the intensity of intraamniotic inflammation Goto Sponge NotDistinct Permalink

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Attributes	Values
rdf:type	skos:Concept http://linked.opendata.cz/ontology/domain/vavai/Vysledek
rdfs:seeAlso	http://dx.doi.org/10.1016/j.ajog.2012.01.004
Description	The objective of the study was to determine whether the bacterial load of genital mycoplasmas and gestation age are related to intraamniotic inflammatory response using the amniotic fluid levels of 18 inflammatory mediators. STUDY DESIGN: A prospective study of 145 women with singleton pregnancies complicated by preterm prelabor rupture of membranes between 24+0 and 36+6 weeks was conducted. Amniotic fluid was obtained from all women by transabdominal amniocentesis. The amounts of genital mycoplasma deoxyribonucleic acid were determined using the threshold cycle value and relative and absolute quantification techniques. A panel of multiple proteins was analyzed simultaneously using multiplex technology. RESULTS: Twenty-four women with the presence of genital mycoplasmas in amniotic fluid were included in the final analyses. The concentrations of 9 of the 18 evaluated proteins in the amniotic fluid correlated with bacterial load of genital mycoplasmas independent of the quantification technique used. CONCLUSION: The intensity of intraamniotic inflammatory response to genital mycoplasmas decreased with gestational age. The objective of the study was to determine whether the bacterial load of genital mycoplasmas and gestation age are related to intraamniotic inflammatory response using the amniotic fluid levels of 18 inflammatory mediators. STUDY DESIGN: A prospective study of 145 women with singleton pregnancies complicated by preterm prelabor rupture of membranes between 24+0 and 36+6 weeks was conducted. Amniotic fluid was obtained from all women by transabdominal amniocentesis. The amounts of genital mycoplasma deoxyribonucleic acid were determined using the threshold cycle value and relative and absolute quantification techniques. A panel of multiple proteins was analyzed simultaneously using multiplex technology. RESULTS: Twenty-four women with the presence of genital mycoplasmas in amniotic fluid were included in the final analyses. The concentrations of 9 of the 18 evaluated proteins in the amniotic fluid correlated with bacterial load of genital mycoplasmas independent of the quantification technique used. CONCLUSION: The intensity of intraamniotic inflammatory response to genital mycoplasmas decreased with gestational age. (en)
Title	The impact of the microbial load of genital mycoplasmas and gestational age on the intensity of intraamniotic inflammation The impact of the microbial load of genital mycoplasmas and gestational age on the intensity of intraamniotic inflammation (en)
skos:prefLabel	The impact of the microbial load of genital mycoplasmas and gestational age on the intensity of intraamniotic inflammation The impact of the microbial load of genital mycoplasmas and gestational age on the intensity of intraamniotic inflammation (en)
skos:notation	RIV/00179906:_____/12:10124604!RIV13-MZ0-00179906
http://linked.open...avai/predkladatel	Fakultní nemocnice Hradec Králové
http://linked.open...avai/riv/aktivita	I P
http://linked.open...avai/riv/aktivity	I, P(GA304/09/0494), P(NS10382)
http://linked.open...iv/cisloPeriodika	4
http://linked.open...vai/riv/dodaniDat	2013
http://linked.open...aciTvurceVysledku	Kacerovský, Marian Bolehovská, Radka Plíšková, Lenka
http://linked.open.../riv/druhVysledku	J - Článek v odborném periodiku
http://linked.open...iv/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open...titaPredkladatele	Fakultní nemocnice Hradec Králové
http://linked.open...dnocenehoVysledku	140714
http://linked.open...ai/riv/idVysledku	RIV/00179906:_____/12:10124604
http://linked.open...riv/jazykVysledku	eng - angličtina
http://linked.open.../riv/klicovaSlova	threshold cycle; molecular microbiology; amniotic fluid; onset; rupture; hominis; culture; membranes; preterm labor; clinical-significance; ureaplasma-urealyticum; polymerase-chain-reaction (en)
http://linked.open.../riv/klicoveSlovo	membranes polymerase-chain-reaction culture onset hominis preterm labor ureaplasma-urealyticum rupture amniotic fluid clinical-significance molecular microbiology threshold cycle
http://linked.open...odStatuVydavatele	US - Spojené státy americké
http://linked.open...ontrolniKodProRIV	[B6F6E51E7355]
http://linked.open...i/riv/nazevZdroje	American Journal of Obstetrics and Gynecology
http://linked.open...in/vavai/riv/obor	FK
http://linked.open...ichTvurcuVysledku	3 (xsd:int)
http://linked.open...cetTvurcuVysledku	7 (xsd:int)
http://linked.open...vavai/riv/projekt	Morphological changes of the fetal thymus and adrenal glands on ultrasound as a marker the systemic fetal inflammatory response syndrome Identification of biomarkers of intraamniotic inflammation and the systemic fetal response syndrome in amniotic fluid: proteomic approach
http://linked.open...UplatneniVysledku	2012
http://linked.open...v/svazekPeriodika	206
http://linked.open...iv/tvurceVysledku	Kacerovský, Marian Bolehovská, Radka Jacobsson, Bo Plíšková, Lenka Hougaard, David M. Skogstrand, Kristin Tsiartas, Panagiotis
http://linked.open...ain/vavai/riv/wos	000302266000029
issn	0002-9378
number of pages	8 (xsd:int)
http://bibframe.org/vocab/doi	10.1016/j.ajog.2012.01.004
is http://linked.open...avai/riv/vysledek of	The impact of the microbial load of genital mycoplasmas and gestational age on the intensity of intraamniotic inflammation

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