About: Morphological changes of the fetal thymus and adrenal glands on ultrasound as a marker the systemic fetal inflammatory response syndrome

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About: Morphological changes of the fetal thymus and adrenal glands on ultrasound as a marker the systemic fetal inflammatory response syndrome Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Projekt, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/domain/vavai/Projekt
rdfs:seeAlso	http://www.isvav.cz/projectDetail.do?rowId=GA304/09/0494
Description	The systemic fetal inflammatory response syndrome (FIRS) is a condition, which is usually subclinical, and is characterized by fetal immune systém activation. The presence of FIRS is known to be strongly associated with preterm labor, particularly in the setting of preterm premature rupture of the membranes. FIRS is associated with perinatal morbidity and death independent of its association with premature birth. FIRS is defined by elevations in the level interleukin 6 or funisitis or both. Infection and other stress processes may cause acute thymic involution by the activation of the hypothalamo-pituitary-adrenal axis. Activation of the adrenal glands of the fetus and acute thymic involution are associated with morphological changes in these organs. The size of the fetal thymus is decreased but the adrenal glands are increased in size in women with chorioamnionitis. Measurement of the fetal thymus and adrenal glands might therefore allow an early diagnosis of FIRS in cases of premature preterm rupture of the membranes. (en) 1.Zjištění rozdílu ultrazvukové velikosti fetálního thymu a fetální nadledvinky u plodů s FIRS ve srovnání se zdravými plody. 2.Možnosti využití poměru velikostí fetálního thymu a fetální nadledvinky k diagnostice FIRS. 3.Možnosti využití poměru kortizolu/DHEAS z fetální krve k diagnostice FIRS.
Title	Morphological changes of the fetal thymus and adrenal glands on ultrasound as a marker the systemic fetal inflammatory response syndrome (en) Morfologické změny thymu a nadledvinek v ultrazvukovém obraze plodu jako marker syndromu fetální zánětlivé odpovědi
skos:notation	GA304/09/0494
http://linked.open...avai/cep/aktivita	Standard projects
http://linked.open...kovaStatniPodpora	http://linked.opendata.cz/resource/domain/vavai/projekt/GA304%2F09%2F0494/celkovaStatniPodpora
http://linked.open...ep/celkoveNaklady	http://linked.opendata.cz/resource/domain/vavai/projekt/GA304%2F09%2F0494/celkoveNaklady
http://linked.open...datumDodatniDoRIV	2015-03-02 (xsd:date)
http://linked.open...i/cep/druhSouteze	VS - Veřejná soutěž ve výzkumu a vývoji
http://linked.open...ep/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open.../cep/fazeProjektu	91497137
http://linked.open...ai/cep/hlavniObor	FK - Gynekologie a porodnictví
http://linked.open...hodnoceniProjektu	V - Vynikající výsledky (s mezinárodním významem apod.). Zároveň byly splněny cíle a předpokládané výsledky uvedené ve smlouvě / rozhodnutí o poskytnutí podpory.
http://linked.open...vai/cep/kategorie	ZV - Základní výzkum
http://linked.open.../cep/klicovaSlova	thymus plodu; nadledvinky plodu; syndrom zánětlivé odpovědi plodu; ultrazvuk (en)
http://linked.open...ep/partnetrHlavni	Lékařská fakulta v Hradci Králové
http://linked.open...inujicichPrijemcu	0 (xsd:int)
http://linked.open...cep/pocetPrijemcu	1 (xsd:int)
http://linked.open...ocetSpoluPrijemcu	1 (xsd:int)
http://linked.open.../pocetVysledkuRIV	16 (xsd:int)
http://linked.open...enychVysledkuVRIV	16 (xsd:int)
http://linked.open...lneniVMinulemRoce	2011-04-16 (xsd:date)
http://linked.open.../prideleniPodpory	http://linked.opendata.cz/resource/domain/vavai/cep/prideleniPodpory/304%2F09%2F0494
http://linked.open...iciPoslednihoRoku	2011
http://linked.open...atUdajeProjZameru	2012
http://linked.open.../vavai/cep/soutez	SGA02009GA-ST
http://linked.open...usZobrazovaneFaze	DUU
http://linked.open...ai/cep/typPojektu	P - Projekt výzkumu a vývoje financovaný ze státního rozpočtu
http://linked.open...ep/ukonceniReseni	2011-12-31 (xsd:date)
http://linked.open...ep/zahajeniReseni	2009-01-01 (xsd:date)
http://linked.open...jektu+dodavatelem	Řešení projektu proběhlo výtečně, jak z hlediska odborného tak i z hlediska čerpání finančních prostředků. (cs) The project was excellent, both in terms of expertise and in terms of disbursement of funds. (en)
http://linked.open...tniCyklusProjektu	ZBKU
http://linked.open.../cep/klicoveSlovo	nadledvinky plodu syndrom zánětlivé odpovědi plodu thymus plodu
is http://linked.open...vavai/riv/projekt of	Amniotic fluid soluble Toll-like receptor 4 in pregnancies complicated by preterm prelabor rupture of the membranes A prediction model of histological chorioamnionitis and funisitis in preterm prelabor rupture of membranes: analyses of multiple proteins in the amniotic fluid Intraamniotic inflammatory response to bacteria: analysis of multiple amniotic fluid proteins in women with preterm prelabor rupture of membranes Intra-Amniotic Inflammatory Response in Subgroups of Women with Preterm Prelabor Rupture of the Membranes Pulsation of the fetal splenic vein - a potential ultrasound marker of histological chorioamnionitis and funisitis in women with preterm prelabor rupture of membranes Amniotic fluid concentrations of soluble scavenger receptor for hemoglobin (sCD163) in pregnancy complicated by preterm premature rupture of the membranes and histologic chorioamnionitis The impact of the microbial load of genital mycoplasmas and gestational age on the intensity of intraamniotic inflammation Soluble Toll-like receptor 1 family members in the amniotic fluid of women with preterm prelabor rupture of the membranes The microbial load with genital mycoplasmas correlates with the degree of histologic chorioamnionitis in preterm PROM Umbilical cord blood levels of cortisol and dehydroepiandrosterone sulfate in preterm prelabor rupture of membrane pregnancies complicated by the presence of histological chorioamnionitis Interleukin 6 v plodové vodě pacientek s předčasným odtokem plodové vody Heat shock protein 70 v plodové vodě u pacientek s předčasným odtokem plodové vody Pentraxin 3 in amniotic fluid as a marker of intra-amniotic inflammation in women with preterm premature rupture of membranes Prenatal diagnosis of an Intertwin Membrane Hematoma Umbilical cord blood concentrations of IL-6, IL-8, and MMP-8 in pregnancy complicated by preterm premature rupture of the membranes and histological chorioamnionitis Ultrasound measurements of the transverse diameter of the fetal thymus in uncomplicated singleton pregnancies
is http://linked.open...vavai/cep/projekt of	http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA304%2F09%2F0494/2009/ico%3A00179906 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA304%2F09%2F0494/2009/orjk%3A11150 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA304%2F09%2F0494/2010/ico%3A00179906 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA304%2F09%2F0494/2010/orjk%3A11150 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA304%2F09%2F0494/2011/ico%3A00179906 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA304%2F09%2F0494/2011/orjk%3A11150 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA304%2F09%2F0494/2012/ico%3A00179906 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/GA304%2F09%2F0494/2012/orjk%3A11150

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