About: Tramadol efficacy in patients with postoperative pain in relation to CYP2D6 and MDR1 polymorphisms     Goto   Sponge   NotDistinct   Permalink

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Description
  • Pharmacokinetics of tramadol and its metabolites is stereoselective and displays high interindividual variability correlating with polymorphic CYP2D6 in the population. Available data provide controversial results regarding the analgesic efficacy of tramadol in subjects with different CYP2D6 genotypes.
  • Pharmacokinetics of tramadol and its metabolites is stereoselective and displays high interindividual variability correlating with polymorphic CYP2D6 in the population. Available data provide controversial results regarding the analgesic efficacy of tramadol in subjects with different CYP2D6 genotypes. (en)
Title
  • Tramadol efficacy in patients with postoperative pain in relation to CYP2D6 and MDR1 polymorphisms
  • Tramadol efficacy in patients with postoperative pain in relation to CYP2D6 and MDR1 polymorphisms (en)
skos:prefLabel
  • Tramadol efficacy in patients with postoperative pain in relation to CYP2D6 and MDR1 polymorphisms
  • Tramadol efficacy in patients with postoperative pain in relation to CYP2D6 and MDR1 polymorphisms (en)
skos:notation
  • RIV/00064203:_____/12:7994!RIV13-MZ0-00064203
http://linked.open...avai/predkladatel
http://linked.open...avai/riv/aktivita
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  • I, P(GP305/08/P069)
http://linked.open...iv/cisloPeriodika
  • 3
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  • 174834
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  • RIV/00064203:_____/12:7994
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  • analgesia; tramadol; acute pain; polymorphism; arthroscopy; czech population; pharmacokinetics; metabolites; genotype; c3435t; impact (en)
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  • SK - Slovenská republika
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  • [2585DFC8A6AB]
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  • Bratislava Medical Journal - Bratislavské Lekárske listy
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  • 113
http://linked.open...iv/tvurceVysledku
  • Pafko, Pavel
  • Perlik, F.
  • Slanar, O.
  • Vondrackova, H.
  • Dupal, Pavel
  • Matouskova, O.
http://linked.open...ain/vavai/riv/wos
  • 000302385900005
issn
  • 0006-9248
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