About: Genetic rescue of an endangered mammal by cross-species nuclear transfer using post mortem somatic cells     Goto   Sponge   NotDistinct   Permalink

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  • Since the advent of procedures for cloning animals conservation biologists have proposed using this technology to preserve endangered mammals. Here we report the successful cloning of a wild endangered animal Ovis orientalis musimon using oocytes collected from a closely related domesticated species Ovis aries. We injected enucleated sheep oocytes with granulosa cells collected from two female mouflons found dead in the pasture. Blastocyst-stage cloned embryos transferred into sheep foster mothers r mothers established two pregnancies one of which produced an apparently normal mouflon. Our findings support the use of cloning for the expansion of critically endangered populations.
  • Since the advent of procedures for cloning animals conservation biologists have proposed using this technology to preserve endangered mammals. Here we report the successful cloning of a wild endangered animal Ovis orientalis musimon using oocytes collected from a closely related domesticated species Ovis aries. We injected enucleated sheep oocytes with granulosa cells collected from two female mouflons found dead in the pasture. Blastocyst-stage cloned embryos transferred into sheep foster mothers r mothers established two pregnancies one of which produced an apparently normal mouflon. Our findings support the use of cloning for the expansion of critically endangered populations. (en)
Title
  • Genetic rescue of an endangered mammal by cross-species nuclear transfer using post mortem somatic cells
  • Genetic rescue of an endangered mammal by cross-species nuclear transfer using post mortem somatic cells (en)
skos:prefLabel
  • Genetic rescue of an endangered mammal by cross-species nuclear transfer using post mortem somatic cells
  • Genetic rescue of an endangered mammal by cross-species nuclear transfer using post mortem somatic cells (en)
skos:notation
  • RIV/00027014:_____/01:00000041!RIV/2002/GA0/M02002/N
http://linked.open.../vavai/riv/strany
  • 962-964
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GV524/96/K162)
http://linked.open...iv/cisloPeriodika
  • 10
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 681068
http://linked.open...ai/riv/idVysledku
  • RIV/00027014:_____/01:00000041
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • nuclear transfer; cloning; somatic cells (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • US - Spojené státy americké
http://linked.open...ontrolniKodProRIV
  • [8CFF59705007]
http://linked.open...i/riv/nazevZdroje
  • Nature biotechnology
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...ocetUcastnikuAkce
http://linked.open...nichUcastnikuAkce
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 19
http://linked.open...iv/tvurceVysledku
  • Fulka jr., Josef
  • Loi, Pasqualino
  • Ptak, Grazyna
  • Barboni, Barbara
issn
  • 1087-0156
number of pages
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