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Description
  • A frequent cause of death in Friedreich's ataxia patients is cardiomyopathy, but the molecular alterations underlying this condition are unknown. We performed 2-DE to characterize the changes in protein expression of hearts using the muscle creatine kinase frataxin conditional knockout (KO) mouse.
  • A frequent cause of death in Friedreich's ataxia patients is cardiomyopathy, but the molecular alterations underlying this condition are unknown. We performed 2-DE to characterize the changes in protein expression of hearts using the muscle creatine kinase frataxin conditional knockout (KO) mouse. (en)
  • Proteomická analýza srdeční hypertrofie u myšího modelu (Frataxin knockout) Friedrichsovy ataxie odhalila poruchy proteinu energetického a obecného metabolismu, proteinu cytoskeletu, buněčné struktury stresové odpovědi jako patogenetický faktor rozvoje choroby. (cs)
Title
  • Proteomic analysis of hearts from frataxin knockout mice : marked rearrangement of energy metabolism, a response to cellular stress and altered expression of proteins involved in cell structure, motility and metabolism
  • Proteomická analýza srdeční hypertrofie u myšího modelu (cs)
  • Proteomic analysis of hearts from frataxin knockout mice : marked rearrangement of energy metabolism, a response to cellular stress and altered expression of proteins involved in cell structure, motility and metabolism (en)
skos:prefLabel
  • Proteomic analysis of hearts from frataxin knockout mice : marked rearrangement of energy metabolism, a response to cellular stress and altered expression of proteins involved in cell structure, motility and metabolism
  • Proteomická analýza srdeční hypertrofie u myšího modelu (cs)
  • Proteomic analysis of hearts from frataxin knockout mice : marked rearrangement of energy metabolism, a response to cellular stress and altered expression of proteins involved in cell structure, motility and metabolism (en)
skos:notation
  • RIV/00023736:_____/08:00007631!RIV09-MZ0-00023736
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(GA204/07/0830), P(GD204/03/H066), P(LC06044), P(LC545), P(NR8317), P(NR8930), Z(MZ0UHKT2005)
http://linked.open...iv/cisloPeriodika
  • 8
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
http://linked.open...iv/duvernostUdaju
http://linked.open...titaPredkladatele
http://linked.open...dnocenehoVysledku
  • 390640
http://linked.open...ai/riv/idVysledku
  • RIV/00023736:_____/08:00007631
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • proteomics; iron metabolism; Friedrich´s ataxia (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • DE - Spolková republika Německo
http://linked.open...ontrolniKodProRIV
  • [C7876308ECD5]
http://linked.open...i/riv/nazevZdroje
  • Proteomics
http://linked.open...in/vavai/riv/obor
http://linked.open...ichTvurcuVysledku
http://linked.open...cetTvurcuVysledku
http://linked.open...vavai/riv/projekt
http://linked.open...UplatneniVysledku
http://linked.open...v/svazekPeriodika
  • 8
http://linked.open...iv/tvurceVysledku
  • Vyoral, Daniel
  • Koenig, M.
  • Richardson, D.
  • Šuťák, R.
  • Abul, K.
  • Pucci, H.
  • Whitnall, M.
  • Xu, X.
http://linked.open...ain/vavai/riv/wos
  • 000255314300017
http://linked.open...n/vavai/riv/zamer
issn
  • 1615-9853
number of pages
is http://linked.open...avai/riv/vysledek of
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