About: Interaction of common sequence variants and selected risk factors in determination of HDL cholesterol levels.     Goto   Sponge   NotDistinct   Permalink

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  • We analysed five SNPs (ABCA1 g.1051G>A, APOA1 g.-75G>A, CETP g.-629C>A, HNF1A g.102A>C, and LIPG g.584C>T, apoE) in 743 individuals (340 men and 403 women) with high mean TG and LDL-c levels. Only CETP genotype was associated with HDL-c levels (p=0.004). Possible interplay between APOA1 and menopause (p=0.002) and ABCA1 and APOE isoforms (p=0.017) on HDL-c concentration was suggested.
  • We analysed five SNPs (ABCA1 g.1051G>A, APOA1 g.-75G>A, CETP g.-629C>A, HNF1A g.102A>C, and LIPG g.584C>T, apoE) in 743 individuals (340 men and 403 women) with high mean TG and LDL-c levels. Only CETP genotype was associated with HDL-c levels (p=0.004). Possible interplay between APOA1 and menopause (p=0.002) and ABCA1 and APOE isoforms (p=0.017) on HDL-c concentration was suggested. (en)
Title
  • Interaction of common sequence variants and selected risk factors in determination of HDL cholesterol levels.
  • Interaction of common sequence variants and selected risk factors in determination of HDL cholesterol levels. (en)
skos:prefLabel
  • Interaction of common sequence variants and selected risk factors in determination of HDL cholesterol levels.
  • Interaction of common sequence variants and selected risk factors in determination of HDL cholesterol levels. (en)
skos:notation
  • RIV/00023001:_____/10:00002325!RIV11-MZ0-00023001
http://linked.open...avai/riv/aktivita
http://linked.open...avai/riv/aktivity
  • P(NS10327), V
http://linked.open...iv/cisloPeriodika
  • 9
http://linked.open...vai/riv/dodaniDat
http://linked.open...aciTvurceVysledku
http://linked.open.../riv/druhVysledku
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  • 264378
http://linked.open...ai/riv/idVysledku
  • RIV/00023001:_____/10:00002325
http://linked.open...riv/jazykVysledku
http://linked.open.../riv/klicovaSlova
  • HDL cholesterol; polymorphism; risk factor; ABCA1; APOA1; CETP; HNF1A; LIPG (en)
http://linked.open.../riv/klicoveSlovo
http://linked.open...odStatuVydavatele
  • NL - Nizozemsko
http://linked.open...ontrolniKodProRIV
  • [506F2A07C902]
http://linked.open...i/riv/nazevZdroje
  • Clinical biochemistry
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http://linked.open...vavai/riv/projekt
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http://linked.open...v/svazekPeriodika
  • 43
http://linked.open...iv/tvurceVysledku
  • Hubáček, Jaroslav
  • Zvárová, J.
  • Vrablík, M.
  • Češka, R.
  • Hirschfeldova, K.
  • Sedova, M.
  • Svobodova, H.
http://linked.open...ain/vavai/riv/wos
  • 000278161200009
issn
  • 0009-9120
number of pages
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