About: Prolactin and rheumatoid arthritis     Goto   Sponge   NotDistinct   Permalink

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  • I: Prolactin participates in the etiopathogenesis of autoimmune disorders. II: Prolactin is producted by inflammation-activated peripheral blood cells. III: Several works are available which evidence its presence in the synovial fluid and correlation with its serum levels or the activity of the underlying condition - rheumatoid arthritis. IV. PRL serum levels and presence in the synovial fluid will be established by a radioimmunoanalytical method. RA activity will be evaluated using DAS score. (en)
  • I: Prolaktin se účastní etiopatogeneze autoimunitních chorob. II: Prolaktin je produkován zánětem aktivovaným buňkami periferní krve. III: Existuje několik prací prokazující jeho existenci v synoviální tekutině, případně korelaci s jeho sérovými hladinami, respektive aktivitou základního onemocnění -revmatoidní artritidou. IV. Sérové hladiny a přítomnost PRL v kloubní tekutině bude stanovena raioimunoanalytickou metodou. Aktivita revmatoidní artritidy bude hodnocena DAS-skóre.
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  • Prolactin and rheumatoid arthritis (en)
  • Prolaktin a revmatoidní artritida
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  • NR9292
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  • rheumatoid arthritis; prolactin; synovial fluid; DAS score; anti-CCP; rheumatoid factor (en)
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  • Prolactin levels in serum as well as in synovial fluid are higher in RA than in degenerative joint disease.Synovial fluid prolactin levels correlate with disease activity of RA.We detected protective genotype of PRLgene for systemic sclerosis development (en)
  • Hladina prolaktinu v séru i v synoviální tekutině je vyšší u RA než u degenerativního kloubního onemocnění. Hladina prolaktinu v synoviální tekutině koreluje s aktivitou RA. Zjistili jsme protektivní genotyp PRL genu pro rozvoj syst.sklerodermie. (cs)
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  • rheumatoid arthritis
  • DAS score
  • anti-CCP
  • prolactin
  • synovial fluid
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