About: Pharmacogenetics aspects of efficacy and safety in medicament therapy in IBD     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Projekt, within Data Space : linked.opendata.cz associated with source document(s)

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Description
  • The project monitors of the participation some genes (TPMT,ITPA,MDR-1), which are responsible for xenobiotics metabolism, on the occurrence of a side effects and low efficacy of corticosteroids and thiopurins in patiens with inflammatory bowel disease (en)
  • Projekt monitoruje podíl polymorfismu některých genů (TPMT, ITPA, MDR-1), odpovědných za metabolizmus xenobiotik, na výskyt nežádoucích účinků a nízké efektivitě léčby kortikosteroidy a thiopuriny u nemocných s idiopatickými střevními záněty.
Title
  • Pharmacogenetics aspects of efficacy and safety in medicament therapy in IBD (en)
  • Farmakogenetické aspekty účinnosti a bezpečnosti medikamentózní terapie idiopatických střevních zánětů
skos:notation
  • NR9094
http://linked.open...avai/cep/aktivita
http://linked.open...kovaStatniPodpora
http://linked.open...ep/celkoveNaklady
http://linked.open...datumDodatniDoRIV
http://linked.open...i/cep/druhSouteze
http://linked.open...ep/duvernostUdaju
http://linked.open.../cep/fazeProjektu
http://linked.open...ai/cep/hlavniObor
http://linked.open...hodnoceniProjektu
http://linked.open...vai/cep/kategorie
http://linked.open.../cep/klicovaSlova
  • Inflammatory bowel disase; Crohn´s disease; ulcerative colitis; pharmacogenetics; genetic polymorph; thiopurinmethyltransferase; inosinetriphosphate; P-glycoprotein (en)
http://linked.open...ep/partnetrHlavni
http://linked.open...inujicichPrijemcu
http://linked.open...cep/pocetPrijemcu
http://linked.open...ocetSpoluPrijemcu
http://linked.open.../pocetVysledkuRIV
http://linked.open...enychVysledkuVRIV
http://linked.open...lneniVMinulemRoce
http://linked.open.../prideleniPodpory
http://linked.open...iciPoslednihoRoku
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http://linked.open.../vavai/cep/soutez
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http://linked.open...ai/cep/typPojektu
http://linked.open...ep/ukonceniReseni
http://linked.open...ep/zahajeniReseni
http://linked.open...jektu+dodavatelem
  • Výsledkem řešení projetu je zavedení rutinní genotypizace TPMT před zahájením léčby azathioprinem u pacientů ls Crohnovou chorobou a také průkaz nepřínosnosti stanovování MDR1 a ITPA v rutinní klinické praxi. (cs)
  • Main outcome is development and introduction of routine screening genotypization of TPMT at the beginning of the azathioprine administration in patients suffering Crohn disease and also the proof of inefficiacy of MDR1 and IPTP in clinical conditions.. (en)
http://linked.open...tniCyklusProjektu
http://linked.open.../cep/klicoveSlovo
  • pharmacogenetics
  • ulcerative colitis
  • Crohn´s disease
  • genetic polymorph
  • inosinetriphosphate
  • thiopurinmethyltransferase
  • Inflammatory bowel disase
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