About: MOLECULAR MECHANISMS OF ANTITUMOR EFFECTS OF HMG-CoA REDUCTASE INHIBITORS     Goto   Sponge   NotDistinct   Permalink

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Description
  • Study of mechanisms of antitumor effects of HMG-CoA reductase inhibitors on experimental model of pancreatic adenocarcinoma. (en)
  • Studium mechanismů protinádorových účinků inhibitorů HMG-CoA reduktázy na experimentálním modelu adenokarcinomu pankreatu.
Title
  • MOLECULAR MECHANISMS OF ANTITUMOR EFFECTS OF HMG-CoA REDUCTASE INHIBITORS (en)
  • Molekulární mechanismy protinádorových účinků inhibitorů HMG-CoA reduktázy
skos:notation
  • NR8132
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  • HMG-CoA reductase; statins; pancreatic cancer; apoptosis; cell proliferation; cholesterol; signal transduction; cell signalisation (en)
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  • Výzkum prokázal nespornou roli nukleárního faktoru kappa B v patogenezi nádorových a zánětlivých chorob a odhalil četné možnosti modulace jeho funkce. (cs)
  • Intensive research has proved its indisputable role in pathogenesis of particularly inflammatory and tumor disease and revealed many possibilities in the modulation of its function. (en)
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  • apoptosis
  • cell proliferation
  • cholesterol
  • signal transduction
  • pancreatic cancer
  • statins
  • HMG-CoA reductase
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