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| Description
| - Determination of acetylcholinesterase activity, pharmacokinetics and adverse events of galanthamine with L-carnitine, cyclosporine A, nitrendipine and nitroarginine metylester. The aim is contribute to improve therapy of cognitive disordes. (en)
- V experimentu bude sledována anticholinesterázová aktivita, farmakokinetika a nežádoucí účinky galantaminu v interakci s L-karnitinem, cyklosporinem A, nitrendipinem a nitroarginin metylesterem. Cílem je zlepšit efektivitu léčby u kognitivních poruch.
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| Title
| - Interactions of galanthamine with modulators of membrane transport in the central nervous system (en)
- Interakce galantaminu s modulátory membránového transportu na úrovni centrálního nervového systému
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| skos:notation
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| http://linked.open...avai/cep/aktivita
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| http://linked.open...kovaStatniPodpora
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| http://linked.open...ep/celkoveNaklady
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| http://linked.open...datumDodatniDoRIV
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| http://linked.open...i/cep/druhSouteze
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| http://linked.open...ep/duvernostUdaju
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| http://linked.open.../cep/fazeProjektu
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| http://linked.open...ai/cep/hlavniObor
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| http://linked.open...hodnoceniProjektu
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| http://linked.open...vai/cep/kategorie
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| http://linked.open.../cep/klicovaSlova
| - acetylcholinesterase; cognitive drug; galanthamin; interaction; neuroprotection; pharmacokinetics; targeting (en)
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| http://linked.open...ep/partnetrHlavni
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| http://linked.open...inujicichPrijemcu
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| http://linked.open...cep/pocetPrijemcu
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| http://linked.open...ocetSpoluPrijemcu
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| http://linked.open.../pocetVysledkuRIV
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| http://linked.open...enychVysledkuVRIV
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| http://linked.open...okUkonceniPodpory
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| http://linked.open...okZahajeniPodpory
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| http://linked.open...iciPoslednihoRoku
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| http://linked.open...atUdajeProjZameru
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| http://linked.open.../vavai/cep/soutez
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| http://linked.open...usZobrazovaneFaze
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| http://linked.open...ai/cep/typPojektu
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| http://linked.open...jektu+dodavatelem
| - Comparison of repeated administr.of L-carnitine,cyklosporinuA+nitrendipinu on the anticholinesterázovou activity of galanthamin.was conducted.The both (CRT,CsA) didnt influence peripheral activity of GAL.The centr.effect of GAL was more augmented by CsA. (en)
- Provedeno srovnání opakovaného podání L-carnitine,cyklosporinuA a nitrendipinu na anticholinesterázovou aktivitu galanthaminu.Jak CRT, tak CsA neovlivnily perifrní aktivitu GAL.Centr.účinek GAL byl více zesilován CsA ve srovnání s CRT. (cs)
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| http://linked.open...tniCyklusProjektu
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| http://linked.open.../cep/klicoveSlovo
| - acetylcholinesterase
- interaction
- pharmacokinetics
- cognitive drug
- galanthamin
- neuroprotection
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| is http://linked.open...vavai/riv/projekt
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| is http://linked.open...vavai/cep/projekt
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