About: Inherited disorders of hematopoessis

Facets (new session)
Description
Metadata
Settings
- owl:sameAs
- Inference Rule:

About: Inherited disorders of hematopoessis Goto Sponge NotDistinct Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Projekt, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/domain/vavai/Projekt
rdfs:seeAlso	http://www.isvav.cz/projectDetail.do?rowId=NE6689
Description	Molecular genetic studies of the pathogenesis of Diamond-Blackfan anemia (DBA). Genetic analysis of candidate genes for DBA/ the role of haploinsuficiency of ribosomal protein S19 (RPS) in human hematopoiesis Murine model of the human hematopoiesis of DBA patients/ the role of modulatory cytokines on DBA hematopoiesis engrafted in NOD/SCID mice. Mechanismus of pathogenesis of primary familial and congenital polycythemia (PFCP)/ genetic analyses of candidate genes for PFCP, novel diagnostic approaches. (en) Studium mechanismů patogeneze Diamond-Blackfanovy anemie (DBA). Genetická analýza kandidátních genů proDBA/ studium vlivu haploinsuficience RPS19 na lidskou hematopoezu. Myší model na lidské hematopoezy pacientů s DBA/vliv růstových faktorů na hematopoetické buňky na modelu NOD/SCID in vivo. Studium mechanismů patogeneze primární familiální a kongenitální polycytemie (PFCP)/ genetická analýza a nové diagnostické metody.
Title	Inherited disorders of hematopoessis (en) Vrozené defekty hematopoesy
skos:notation	NE6689
http://linked.open...avai/cep/aktivita	Research and development in the sphere of paediatrics and genetics
http://linked.open...kovaStatniPodpora	http://linked.opendata.cz/resource/domain/vavai/projekt/NE6689/celkovaStatniPodpora
http://linked.open...ep/celkoveNaklady	http://linked.opendata.cz/resource/domain/vavai/projekt/NE6689/celkoveNaklady
http://linked.open...datumDodatniDoRIV	2004-07-12 (xsd:date)
http://linked.open...i/cep/druhSouteze	VS - Veřejná soutěž ve výzkumu a vývoji
http://linked.open...ep/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open.../cep/fazeProjektu	1488803
http://linked.open...ai/cep/hlavniObor	FG - Pediatrie
http://linked.open...hodnoceniProjektu	U - Uspěl podle zadání, tj. byly splněny cíle a jeho předpokládané výsledky uvedené ve smlouvě / rozhodnutí o poskytnutí podpory
http://linked.open.../cep/klicovaSlova	Diamond Blackfan anemia;Primary polycythemia;Erythropoietin;Ribosomal protein S19;NOD/SCID mice;Stem cells;Differentiation;Mutation (en)
http://linked.open...ep/partnetrHlavni	Ústav hematologie a krevní transfúze
http://linked.open...inujicichPrijemcu	0 (xsd:int)
http://linked.open...cep/pocetPrijemcu	1 (xsd:int)
http://linked.open...ocetSpoluPrijemcu	1 (xsd:int)
http://linked.open.../pocetVysledkuRIV	17 (xsd:int)
http://linked.open...enychVysledkuVRIV	17 (xsd:int)
http://linked.open...iciPoslednihoRoku	2004
http://linked.open...atUdajeProjZameru	2004
http://linked.open.../vavai/cep/soutez	SMZ0NE2001
http://linked.open...usZobrazovaneFaze	DUU
http://linked.open...ai/cep/typPojektu	P - Projekt výzkumu a vývoje financovaný ze státního rozpočtu
http://linked.open...jektu+dodavatelem	Přínosem projektu je další poznání patogeneze DBA. (cs)
http://linked.open...tniCyklusProjektu	ZBKU
http://linked.open.../cep/klicoveSlovo	Erythropoietin Differentiation Stem cells Primary polycythemia Diamond Blackfan anemia NOD/SCID mice Ribosomal protein S19
is http://linked.open...vavai/riv/projekt of	Elevated thrombopoietin (Tpo) levels and mutations in Tpo receptor c-mpl in patients with Diamond-Blackfan Anemia (DBA) : a potential role of Tpo in DBA pathogenesis. Expression of genes regulating angiogenesis in human circulating hematopoietic cord blood CD34+/CD133+ cells The effect of expression of ribosomal protein S19 mutations found in Diamond-Blackfan anemia patients on K562 cell line. Diamond Blackfan anemia stem cells fail to repopulate erythropoiesis in NOD/SCID mice. Exprese pro-angiogenního faktoru angiopoietinu-2 v CD34+buňkách pupečníkové krve Inhibition of Smad5 in human hematopoietic progenitors blocks erythroid differentiation induced by BMP4. Inhibition of Smad5 in human hematopoietic progenitors blocks erythroid differentiation induced by BMP4. Inhibition of Smad5 in Human Hematopoietic Progenitors Blocks Erythroid Differentiation Induced by BMP4 (2) Inhibition of SMAD5 in human hematopoietic progenitors blocks erythroid differentiation induced by BMP4 (1) K562 cells transfected with mutant ribosomal protein S19 (RPS19) have a limited protein translation rate suggesting a dominant negative effect of RPS19 mutations in Diamond-Blackfan anemia. Differential sensitivity of polycythemia vera (PV) and primary familial and congenital polycythemia (PFCP) erythroid progenitors to stem cell factor and erythropoietin. Stability and expression of human MDR1 in retroviral vectors for gene therapy. Molecular basis of Diamond-Blackfan anemia : what we have learnt so far? Mitochondria Play a Central Role in Apoptosis Induced by alfa-Tocopheryl Succinate, an Agent with Antineoplastic Activity: Comparison with Receptor-Mediated Pro-Apoptotic Signaling Transcription factor GATA-4 is not involved in Diamond-Blackfan anaemia. Transcription factor GATA-4 is not mutated in patients with Diamond-Blackfan anemia. TRAIL (Apo2L) supresses growth of primary human leukemia and myelodysplasia progenitors.
is http://linked.open...vavai/cep/projekt of	http://linked.opendata.cz/resource/domain/vavai/cep/ucast/NE6689/2007/ico%3A00023736 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/NE6689/2007/orjk%3A11110 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/NE6689/2007/orjk%3A15110 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/NE6689/2001/ico%3A00023736 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/NE6689/2001/orjk%3A11110 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/NE6689/2001/orjk%3A15110 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/NE6689/2002/ico%3A00023736 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/NE6689/2002/orjk%3A11110 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/NE6689/2002/orjk%3A15110 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/NE6689/2003/ico%3A00023736 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/NE6689/2003/orjk%3A15110 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/NE6689/2004/ico%3A00023736 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/NE6689/2004/orjk%3A15110

Faceted Search & Find service v1.16.118 as of Jun 21 2024

Alternative Linked Data Documents: ODE Content Formats:

RDF

ODATA

Microdata

About

OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 24 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software