About: Structural studies of transcriptional regulators of the DeoR and GntR families involved in catabolic repression in Bacillus subtilis.     Goto   Sponge   NotDistinct   Permalink

An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Projekt, within Data Space : linked.opendata.cz associated with source document(s)

AttributesValues
rdf:type
rdfs:seeAlso
Description
  • In many bacteria, the expression of the genes involved in the metabolism of secondary carbon sources is typically repressed in the presence of the most favorable nutrient. This mechanism of regulation, designated carbon catabolite repression, has been extensively studied in B. subtilis. It requires participation of numerous specific repressors and activators controlling the level of transcription of catabolic genes. Transcriptional repressors involved in catabolic repression mainly belong to one of the two large families of prokaryotic transcriptional regulators, GntR and DeoR, respectively. Members of these families share an N-terminal helix-turn-helix DNA-binding domain and and structurally dissimila C-terminal domains that are involved in effector binding and oligomerization. We have recently determined crystal structures of the effector binding domains of two transcriptional repressors from B. subtilis, CggR (central glycolytic genes regulator) and TreR (trehalose operon repressor), belonging t (en)
  • Cílem projektu je získat strukturní informaci o skupině transkripčních represorů účastnících se katabolické represe v bakterii Bacillus subtilis. K určení struktur využijeme metod rentgenové krystalografie.
Title
  • Structural studies of transcriptional regulators of the DeoR and GntR families involved in catabolic repression in Bacillus subtilis. (en)
  • Strukturní studie transkripčních regulátorů rodiny DeoR a GntR účastnících se katabolické represe v bakterii Bacillus subtilis.
skos:notation
  • ME08016
http://linked.open...avai/cep/aktivita
http://linked.open...kovaStatniPodpora
http://linked.open...ep/celkoveNaklady
http://linked.open...datumDodatniDoRIV
http://linked.open...i/cep/druhSouteze
http://linked.open...ep/duvernostUdaju
http://linked.open.../cep/fazeProjektu
http://linked.open...ai/cep/hlavniObor
http://linked.open...hodnoceniProjektu
http://linked.open...vai/cep/kategorie
http://linked.open.../cep/klicovaSlova
  • Transciptional repressor; catabolic repression; Bacillus subtilis; protein crystallography; X-ray crystallography; 3-D structure; crystal structure (en)
http://linked.open...ep/partnetrHlavni
http://linked.open...inujicichPrijemcu
http://linked.open...cep/pocetPrijemcu
http://linked.open...ocetSpoluPrijemcu
http://linked.open.../pocetVysledkuRIV
http://linked.open...enychVysledkuVRIV
http://linked.open...lneniVMinulemRoce
http://linked.open.../prideleniPodpory
http://linked.open...iciPoslednihoRoku
http://linked.open...atUdajeProjZameru
http://linked.open.../vavai/cep/soutez
http://linked.open...usZobrazovaneFaze
http://linked.open...ai/cep/typPojektu
http://linked.open...ep/ukonceniReseni
http://linked.open.../cep/vedlejsiObor
http://linked.open...ep/zahajeniReseni
http://linked.open...jektu+dodavatelem
  • Cílem pětiletého projekt bilaterální spolupráce bylo získat strukturní informaci o skupině transkripčních regulátorů účastnících se kataboiické represe v bakterii Bacillus subtilis. Výsledkem projektu je šest trojrozměrných struktur represorů CggR, AraR a DeoR. Získané výsledky, které výrazně přispěly k pochopení mechanismů genové regulace, byly publikovány v odborných publikacích. (cs)
  • The aim of a five-year project of bilateral collaboration was to obtain structural information on group of transcriptional regulators in bacteria Bacilus subtilis. Six three-dimensional structures of CggR, AraR and DeoR repressors were determined. Obtained results, which are crucial for understanding mechanisms of gene regulation, were published in scientific journals. (en)
http://linked.open...tniCyklusProjektu
http://linked.open.../cep/klicoveSlovo
  • Bacillus subtilis
  • X-ray crystallography
  • protein crystallography
  • 3-D structure
  • catabolic repression
  • Transciptional repressor
is http://linked.open...vavai/riv/projekt of
is http://linked.open...vavai/cep/projekt of
Faceted Search & Find service v1.16.118 as of Jun 21 2024


Alternative Linked Data Documents: ODE     Content Formats:   [cxml] [csv]     RDF   [text] [turtle] [ld+json] [rdf+json] [rdf+xml]     ODATA   [atom+xml] [odata+json]     Microdata   [microdata+json] [html]    About   
This material is Open Knowledge   W3C Semantic Web Technology [RDF Data] Valid XHTML + RDFa
OpenLink Virtuoso version 07.20.3240 as of Jun 21 2024, on Linux (x86_64-pc-linux-gnu), Single-Server Edition (126 GB total memory, 110 GB memory in use)
Data on this page belongs to its respective rights holders.
Virtuoso Faceted Browser Copyright © 2009-2024 OpenLink Software