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| Description
| - As modern medicine evolves towards quantitative and molecular based science, biophotonics is envisioned to play an increasingly important role in multiple areas of medicine, contributing to quality of health care, reduction of health care costs, and sustainability of the medical care in the ageing society. The proposal aims to advance research in selected areas of nanobiophotonics with focus on photonic molecular biosensors based on plasmonic nanostructures. The main areas of research in this project include research into plasmonic phenomena on metallic nanostructures, development of novel tools for analysis and design of plasmonic nanostructures, fabrication and experimental characterization of plasmonic nanostructures with potential for surface plasmon resonance (SPR) and surface-enhanced Raman scattering (SERS) sensing, interfacing biomolecules with inorganic nanostructures and investigation of interactions between such biophotonic structures and biological samples, and realization of SPR and SERS biosensors for detection of biomarkers of onco-hematological diseases. (en)
- Biofotonika představuje jednu z nejrychleji se rozvíjejících vědeckých disciplín současnosti. Očekává se, že biofotonika se bude významně podílet na formování nové generace nástrojů a metod pro medicinální výzkum a diagnostiku a přispěje tak k efektivnější, kvalitnější a dlouhodobě udržitelné zdravotní péči. Navrhovaný projekt je projektem základního orientovaného výzkumu v oblasti biofotoniky se zaměřením na biosenzory založené na fotonických nanostrukturách. Hlavní výzkumné oblasti tohoto projektu zahrnují jak výzkum fotonických jevů na kovových nanostrukturách s povrchovými plasmony a nových nástrojů pro jejich teoretickou a analýzu, tak propojení těchto nanostruktur s biomolekulami a studiu interakcí mezi biofotonickými nanostrukturami a biologickými vzorky. Projekt dále zahrnuje přípravu a experimentální charakterizaci speciálních nanostruktur pro nové typy biosenzorů na bázi rezonance povrchových plasmonů (SPR) a povrchem zesíleného Ramanova rozptylu (SERS) pro detekci biomarkerů onkohematologických onemocnění.
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| Title
| - Nanobiophotonics for future health care (en)
- Nanobiofotonika pro medicínu budoucnosti
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| skos:notation
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| http://linked.open...avai/cep/aktivita
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| http://linked.open...kovaStatniPodpora
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| http://linked.open...ep/celkoveNaklady
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| http://linked.open...datumDodatniDoRIV
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| http://linked.open...i/cep/druhSouteze
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| http://linked.open...ep/duvernostUdaju
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| http://linked.open.../cep/fazeProjektu
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| http://linked.open...ai/cep/hlavniObor
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| http://linked.open...vai/cep/kategorie
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| http://linked.open.../cep/klicovaSlova
| - nanobiophotonics nanophotonics nanotechnology photonic biosensors surface plasmons Raman scattering (en)
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| http://linked.open...ep/partnetrHlavni
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| http://linked.open...inujicichPrijemcu
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| http://linked.open...cep/pocetPrijemcu
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| http://linked.open...ocetSpoluPrijemcu
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| http://linked.open.../pocetVysledkuRIV
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| http://linked.open...enychVysledkuVRIV
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| http://linked.open...lneniVMinulemRoce
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| http://linked.open.../prideleniPodpory
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| http://linked.open...iciPoslednihoRoku
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| http://linked.open...atUdajeProjZameru
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| http://linked.open.../vavai/cep/soutez
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| http://linked.open...usZobrazovaneFaze
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| http://linked.open...ai/cep/typPojektu
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| http://linked.open...ep/ukonceniReseni
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| http://linked.open.../cep/vedlejsiObor
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| http://linked.open...ep/zahajeniReseni
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| http://linked.open...tniCyklusProjektu
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| is http://linked.open...vavai/riv/projekt
of | - Molecularly Imprinted Polymer Waveguides for Direct Optical Detection of Low-Molecular-Weight Analytes
- Plasma levels of aminothiols, nitrite, nitrate, and malondialdehyde in myelodysplastic syndromes in the context of clinical outcomes and as a consequence of iron overload
- The effect of the biological variability of samples on Coomassie blue dye based fast staining for SDS-PAGE in nonfixed gels
- Enhancing Sensitivity of Surface Plasmon Resonance Biosensors by Functionalized Gold Nanoparticles: Size Matters
- Fusing catechol-driven surface anchoring with rapid hetero Diels-Alder ligation
- Functionalized ultra-low fouling carboxy- and hydroxy-functional surface platforms: Functionalization capacity, biorecognition capability and resistance to fouling from undiluted biological media
- Theory, modeling, design and realization of advanced photonic (nano)structures
- Use of label-free protein chips for proteomics of oncohematological diseases
- A facile avenue to conductive polymer brushes via cyclopentadiene-maleimide Diels-Alder ligation
- 3D photonic structure modeling with efficient Fourier modal methods
- Configuration-controlled Au nanocluster arrays on inverse micelle nano-patterns: versatile platforms for SERS and SPR sensors
- Enhanced levels of asymmetric dimethylarginine in a serum of middle age patients with myelodysplastic syndrome
- The effect of reagents mimicking oxidative stress on fibrinogen function
- Enhancement of affinity-based biosensors: effect of sensing chamber geometry on sensitivity
- Plasma proteome changes associated with refractory anemia and refractory anemia with ringed sideroblasts in patients with myelodysplastic syndrome.
- Sensitive Raman spectroscopy of lipids based on drop deposition using DCDR and SERS
- SET-LRP of N-(2-hydroxypropyl)methacrylamide in H2O
- Sensing properties of lattice resonances of 2D metal nanoparticle arrays: An analytical model
- Biofunctionalized gold nanoparticles for SPR-biosensor-based detection of CEA in blood plasma
- Analysis of tunable one-way terahertz surface-magnetoplasmonic InSb waveguides
- Surface plasmon resonance optical cavity enhanced refractive index sensing
- Studies on Fano Resonances in Subwavelength Plasmonic Nanostructures
- Teoretické a experimentální aspekty opálových fotonických krystalů
- Surface states in photonic crystals
- Modal Methods for 3D Modelling of Advanced Photonic Structures
- Complete identification of proteins responsible for human blood plasma fouling on poly(ethylene glycol)-based surfaces
- Compact surface plasmon-enhanced fluorescence biochip
- Improved Coomassie Blue dye-based fast staining protocol for proteins separated by SDS-PAGE.
- Hybrid dielectric plasmonic slot guiding nanostructures — analysis with Fourier modal methods
- Application of Fourier modal methods to simulating novel plasmonic guiding nanostructures
- Analytical approach towards fishnet negative index of refraction
- Assessment of novel ingredients within Fourier modal methods
- Label-free slot-waveguide biosensor for the detection of DNA hybridization
- Plasma protein alterations in the refractory anemia with excess blasts subtype 1 subgroup of myelodysplastic syndrome
- Physics and Design Possibilities of Plasmonic-based Fishnet Metamaterial Structures
- Sledování vrozených a získaných, strukturních a funkčních změn fibrinogenu
- SE(R)RS microspectroscopy of porphyrins on immobilized Au nanoparticles: Testing spectral sensitivity and reproducibility
- SE(R)RS excitation profile of free-base 5,10,15,20-tetrakis(1-methyl-4-pyridyl) porphyrin on immobilized gold nanoparticles
- Real-time label-free monitoring of the cellular response to osmotic stress using conventional and long-range surface plasmons
- Staining of proteins for 2D SDS-PAGE using Coomassie Blue-speed versus sensitivity?
- Consideration of photonic and mass-transfer aspects on the performance of a biosensor based on localized surface plasmons on an array of gold cylinders
- Fibrinogen Šumperk II: dysfibrinogenemia in an individual with two coding mutations
- Fourier Series Based 3D Bi-directional Propagation Algorithm for Integrated Photonics
- A novel natural mutation AalphaPhe98Ile in the fibrinogen coiled-coil affects fibrinogen function
- Opal-based photonic crystals-modeling and realization
- Surfaces resistant to fouling from biological fluids: towards bioactive surfaces for real applications
- Surface states in photonic crystals
- Study and Optimization of Fishnet Metamaterial Structures
- Novel homozygous fibrinogen A alpha chain truncation causes severe afibrinogenemia with life threatening complications in a two-year-old boy
- Novel antifouling self-healing poly(carboxybetaine methacrylamide-co-HEMA) nanocomposite hydrogels with superior mechanical properties
- Nonreciprocal waveguiding EM surfaces and structures for THz region
- Novel types of plasmonic waveguiding structures
- Fermitin-3 fragmentation observed in the platelets of patients with cardiovascular diseases
- Flexible method based on four-beam interference lithography for fabrication of large areas of perfectly periodic plasmonic arrays
- Proteome changes in the plasma of myelodysplastic syndrome patients with refractory anemia with excess blasts subtype 2
- Convenient Method of Micrometer-Scale Excitation of Propagating Surface Plasmons by a Focused Laser Beam
- Diagnosis of Epstein-Barr virus infection in clinical serum samples by an SPR biosensor assay
- Polyethylene-glycol-Stabilized Ag Nanoparticles for Surface-Enhanced Raman Scattering Spectroscopy: Ag Surface Accessibility Studied Using Metalation of Free-Base Porphyrins
- Abnormal fibrinogen Zlín (gamaThr21Ile) with missense mutation causing hypofibrinogenemia
- Abnormal fibrinogen Zlín (.gamma.Thr21Ile) with missense mutation causing hypofibrinogenemia
- Ambiguous Refractive Index Sensitivity of Fano Resonance on an Array of Gold Nanoparticles
- Biosensing enhancement using passive mixing structures for microarray-based sensors
- Two novel mutations in the fibrinogen .gamma. nodule
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| is http://linked.open...vavai/cep/projekt
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