About: Quality and safety of food in relation to colorectal cancer predisposition. A pilot study

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An Entity of Type : http://linked.opendata.cz/ontology/domain/vavai/Projekt, within Data Space : linked.opendata.cz associated with source document(s)

Attributes	Values
rdf:type	http://linked.opendata.cz/ontology/domain/vavai/Projekt
rdfs:seeAlso	http://www.isvav.cz/projectDetail.do?rowId=7F10069
Description	The main aim of the sub-project is to develop a set of methods for assessing safety and quality of food and to identify both beneficial as well as harmful components of food. The focus will be on individual response to both protective and damaging effects of identified nutrients in both healthy and pathological states. We will investigate the role of food quality and dietary habits (assessed by questionnaire) as potential positive or negative factors in the incidence and/or progression of colorectal cancer in the Czech Republic, comparing patients and healthy individuals. The project should discern whether the possible impacts of particular nutrients to health status might be reflected in an alteration of individual levels of DNA damage and/or DNA repair capacity, as assayed in healthy individuals and patients with pre-malignant changes (adenomatous polyposis) and malignancies in the colon. Addressing differences in DNA repair capacity represents an important milestone, as it is strongly involved in (en) The main aim of the sub-project is to develop a set of methods for assessing safety and quality of food and to identify both beneficial as well as harmful components of food. The focus will be on individual response to both protective and damaging effects of identified nutrients in both healthy and pathological states. We will investigate the role of food quality and dietary habits (assessed by questionnaire) as potential positive or negative factors in the incidence and/or progression of colorectal cancer in the Czech Republic, comparing patients and healthy individuals. The project should discern whether the possible impacts of particular nutrients to health status might be reflected in an alteration of individual levels of DNA damage and/or DNA repair capacity, as assayed in healthy individuals and patients with pre-malignant changes (adenomatous polyposis) and malignancies in the colon. Addressing differences in DNA repair capacity represents an important milestone, as it is strongly involved in
Title	Quality and safety of food in relation to colorectal cancer predisposition. A pilot study (en) Quality and safety of food in relation to colorectal cancer predisposition. A pilot study
skos:notation	7F10069
http://linked.open...avai/cep/aktivita	EEA/Norwegian Financial Mechanism
http://linked.open...kovaStatniPodpora	http://linked.opendata.cz/resource/domain/vavai/projekt/7F10069/celkovaStatniPodpora
http://linked.open...ep/celkoveNaklady	http://linked.opendata.cz/resource/domain/vavai/projekt/7F10069/celkoveNaklady
http://linked.open...datumDodatniDoRIV	2011-06-30 (xsd:date)
http://linked.open...i/cep/druhSouteze	RP - Spolufinancování programu ES
http://linked.open...ep/duvernostUdaju	S - Úplné a pravdivé údaje nepodléhající ochraně podle zvláštních právních předpisů
http://linked.open.../cep/fazeProjektu	82556799
http://linked.open...ai/cep/hlavniObor	EB - Genetika a molekulární biologie
http://linked.open...hodnoceniProjektu	U - Uspěl podle zadání, tj. byly splněny cíle a jeho předpokládané výsledky uvedené ve smlouvě / rozhodnutí o poskytnutí podpory
http://linked.open...vai/cep/kategorie	ZV - Základní výzkum
http://linked.open.../cep/klicovaSlova	nutrition; DNA damage; DNA repair; DNA functional repair test; polymorphisms; colorectal cancer (en)
http://linked.open...ep/partnetrHlavni	Ústav experimentální medicíny Akademie věd České republiky, v. v. i.
http://linked.open...inujicichPrijemcu	0 (xsd:int)
http://linked.open...cep/pocetPrijemcu	1 (xsd:int)
http://linked.open...ocetSpoluPrijemcu	0 (xsd:int)
http://linked.open.../pocetVysledkuRIV	2 (xsd:int)
http://linked.open...enychVysledkuVRIV	2 (xsd:int)
http://linked.open...lneniVMinulemRoce	2010-11-09 (xsd:date)
http://linked.open.../prideleniPodpory	http://linked.opendata.cz/resource/domain/vavai/cep/prideleniPodpory/22557%2F2010-611
http://linked.open...iciPoslednihoRoku	2010
http://linked.open...atUdajeProjZameru	2011
http://linked.open...usZobrazovaneFaze	DUU
http://linked.open...ai/cep/typPojektu	P - Projekt výzkumu a vývoje financovaný ze státního rozpočtu
http://linked.open...ep/ukonceniReseni	2010-12-31 (xsd:date)
http://linked.open.../cep/vedlejsiObor	DN - Vliv životního prostředí na zdraví FB - Endokrinologie, diabetologie, metabolismus, výživa
http://linked.open...ep/zahajeniReseni	2010-08-01 (xsd:date)
http://linked.open...jektu+dodavatelem	Hodnocení výsledků řešení ministerstvo neprovádí, neboť podmínkou podpory je, že uchazeč byl vybrán mezinárodním poskytovatelem v souladu s pravidly příslušného programu. Projekt je hodnocen až po jeho schválení mezinárodním poskytovatelem. (cs) Following the condition that the candidate of financial contribution was evaluated and afterwards selected by international provider in accordance with the rules of the program the Ministry of Education, Youth ans Sports does not realize the evaluation of project results. The project is evaluated only after its approval by an international provider (en)
http://linked.open...tniCyklusProjektu	JU
http://linked.open.../cep/klicoveSlovo	nutrition DNA damage DNA repair polymorphisms DNA functional repair test
is http://linked.open...vavai/riv/projekt of	Association Between TAS2R38 Gene Polymorphisms and Colorectal Cancer Risk: A Case-Control Study in Two Independent Populations of Caucasian Origin DNA damage and nucleotide excision repair capacity
is http://linked.open...vavai/cep/projekt of	http://linked.opendata.cz/resource/domain/vavai/cep/ucast/7F10069/2010/ico%3A68378041 http://linked.opendata.cz/resource/domain/vavai/cep/ucast/7F10069/2011/ico%3A68378041

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