About: Recombinant Human EGF-rP64K/Montanide ISA 51 Vaccine     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
rdf:type
rdfs:label
  • Recombinant Human EGF-rP64K/Montanide ISA 51 Vaccine
rdfs:subClassOf
Semantic_Type
  • Amino Acid, Peptide, or Protein
  • Pharmacologic Substance
Preferred_Name
  • Recombinant Human EGF-rP64K/Montanide ISA 51 Vaccine
NCI_META_CUI
  • CL376048
PDQ_Open_Trial_Search_ID
  • 570107
PDQ_Closed_Trial_Search_ID
  • 570107
Legacy_Concept_Name
  • Recombinant_Human_EGF-rP64K_Montanide_ISA_51_Vaccine
FULL_SYN
  • Recombinant Human EGF-rP64K/Montanide ISA 51 VaccinePTNCI
DEFINITION
  • A peptide vaccine preparation, containing recombinant human epidermal growth factor (rEGF) linked to the Neisseria meningitidis-derived recombinant immunogenic carrier protein P64k (rP64k) and mixed with the immunoadjuvant Montanide ISA 51, with potential active immunotherapy activity. Recombinant human EGF-rP64K/Montanide ISA 51 vaccine may trigger a humoral immune response against vaccine rEGF and rP64K and, so, against endogenous EGF. Antibody-mediated inhibition of endogenous EGF binding to its receptor, epithelial growth factor receptor (EGFR), may result in the inhibition of tumor cell proliferation.NCI
code
  • C70674
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