About: IL17 Signaling Pathway     Goto   Sponge   NotDistinct   Permalink

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AttributesValues
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  • IL17 Signaling Pathway
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Semantic_Type
  • Functional Concept
Preferred_Name
  • IL17 Signaling Pathway
UMLS_CUI
  • C1512589
BioCarta_ID
  • h_il17Pathway
ALT_DEFINITION
  • Inflammation is a complex response involving many different cells and signaling molecules, including the secretion of the cytokine IL-17 by activated T cells. IL-17 secretion is restricted to specific subsets of T cells but the receptor for IL-17 is widely expressed throughout the body, including fibroblasts and epithelial cells. Inflammatory responses involving IL-17 probably contribute to arthritis, asthma, skin immune reactions, and autoimmune disorders. Fibroblasts and other cells stimulated by IL-17 are induced themselves to secrete inflammatory and hematopoietic cytokines, including IL-6, IL-8, G-CSF, and Stem Cell Factor (SCF). These cytokines in turn provoke a range of activities, including the stimulation of neutrophil proliferation and differentiation.BIOCARTA
Legacy_Concept_Name
  • IL17_Signaling_Pathway
FULL_SYN
  • IL17 Signaling PathwayPTNCI
  • IL 17 Signaling PathwayPTBIOCARTA
code
  • C39118
is someValuesFrom of
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