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AttributesValues
rdf:type
rdfs:label
  • Hyoscyamine
rdfs:subClassOf
Has_Salt_Form
Concept_In_Subset
Semantic_Type
  • Pharmacologic Substance
Preferred_Name
  • Hyoscyamine
NSC_Code
  • 61808
UMLS_CUI
  • C0596004
CAS_Registry
  • 101-31-5
FDA_UNII_Code
  • PX44XO846X
Contributing_Source
  • FDA
Chemical_Formula
  • C17H23NO3
Legacy_Concept_Name
  • Hyoscyamine
CHEBI_ID
  • CHEBI:17486
FULL_SYN
  • HyoscyaminePTNCI
  • (-)-AtropineSYNCI
  • (S)-AtropineSYNCI
  • Benzeneacetic acid, alpha-(hydroxymethyl)-, 8-methyl-8-azabicyclo(3.2.1)oct-3-yl ester, (3(S)-endo)-SNNCI
  • HYOSCYAMINEPTFDAPX44XO846X
DEFINITION
  • A belladonna alkaloid derivative and the levorotatory form of racemic atropine isolated from the plants Hyoscyamus niger or Atropa belladonna, which exhibits anticholinergic activity. Hyoscyamine functions as a non-selective, competitive antagonist of muscarinic receptors, thereby inhibiting the parasympathetic activities of acetylcholine on the salivary, bronchial, and sweat glands, as well as the eye, heart, bladder, and gastrointestinal tract. These inhibitory effects cause a decrease in saliva, bronchial mucus, gastric juices, and sweat. Furthermore, its inhibitory action on smooth muscle prevents bladder contraction and decreases gastrointestinal motility.NCI
code
  • C29104
sameAs
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